Clinical
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Intercourse at the Time of Implantation Confers Lower Chance of Conception
Couples attempting natural conception were found to have a lower chance of success per cycle when intercourse took place at or around the time of implantation. -
Weight Gain with Contraception
In this prospective cohort study, perceived weight gain was found to be an adequate predictor of actual weight gain. Depot medroxyprogesterone acetate and the contraceptive implant were associated with more weight gain than the copper IUD. -
Reassuring Safety Data about Incretins and CHF
The class of medications used to treat diabetes (and obesity) known as “the incretins” includes several DPP4 inhibitors and GLP1 agonists. These agents have achieved a favorable status in prescribing algorithms because of the combination of their low risk of hypoglycemia, impact upon weight (neutral for DPP4, weight loss for GLP1), and effects on postprandial glucose attributed to glucagon blunting.
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Every-other-day Tadalafil for Lower Urinary Tract Symptoms and Erectile Dysfunction
Although the incidence of erectile dysfunction (ED) and lower urinary tract symptoms (LUTS) both increase with age, there is an as-yet ill-explained independent association of LUTS with ED. That is, within each age decile, more severe LUTS is associated with more severe ED.
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Modifying the Home Environment to Prevent Falls
Falls in the home setting are a commonplace source of serious injury. In the recent past, most studies to address falls have addressed children, disabled persons, or the elderly. There is little information on more general populations, or whether a standardized set of environmental modifications — not designed to address any specific disability — would reduce falls and their consequences.
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Obesity Leads to Overdiagnosis of Airflow Obstruction
Some commonplace disorders can readily misdirect clinicians about the presence of other important diagnoses. For instance, in patients with chronic obstructive pulmonary disease (COPD), deterioration of cardiac function, leading to congestive heart failure, can easily be misinterpreted as worsening COPD since fatigue, exercise, intolerance, and dyspnea are common to both. Could obesity misdirect clinicians in their diagnostic process for COPD? This report from the Veterans Administration system suggests that it can.
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NSAIDS for MI — Exercise Caution
In this issue: Treatment of Pharyngitis; and FDA Actions.
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Infectious Disease Alert Updates
The problem of diagnosing TB in children
How best to treat latent TB?
Transmission risk in smear-negative TB
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Antibiotics for Traveler’s Diarrhea?
Foreign travel is associated with travelers’ diarrhea and the intestinal acquisition of extended-spectrum beta lactamase-producing Enterobacteriaceae, especially when travel is to South Asia. The risk of acquisition of resistant flora was almost doubled when antibiotics were used to treat the episode of diarrhea.
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Ceftolozane/Tazobactam — Formulary Considerations
Information about ceftolozane/tazobactam