Clinical
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Dual Add-on Therapy for Type 2 Diabetes When Metformin is Not Enough
The current (2015) American Diabetes Association guidance for progression of treatment when A1c goals are not attained with metformin implies stepwise initiation of additional monotherapies.
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Chronobiology and Insulin Glargine
The “indication” labeling for insulin glargine (Lantus) simply says, “Administer subcutaneously once daily at any time of day, but at the same time every day.”
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Bipolar Disorder is Associated with New-onset CVD
Although perhaps not widely recognized, bipolar disorder (BPD) is associated with an excessive risk of cardiovascular disease (CVD). Not only is CVD more prevalent, but it occurs as much as a decade earlier than comparators without BPD.
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The Ongoing Search for Biomarkers that Provide Early Identification of Cognitive Impairment
Messenger RNA (mRNA) markers are used for identification of a variety of pathologic processes, most recently including malignant melanoma.
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Reducing Drug-induced Xerostomia with Sorbet
Xerostomia, or dry mouth, is common in senior citizens, partially because of disorders that are directly associated with xerostomia (e.g., Sjogren syndrome, HIV, hepatitis C, diabetes) and, additionally, because numerous pharmacologic treatments seniors receive produce “drying” effects: anticholinergics (e.g., antimuscarinic OAB drugs, tricyclic antidepressants), sympathomimetics (e.g., milnacipran, atomoxetine), or diuretics.
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Help young women transition to adult healthcare
Young women ages 18 to 25 represent a heterogeneous population transitioning from adolescence into adulthood who might present with unique issues and challenges, including a potential gap in healthcare after pediatric healthcare. The American College of Obstetrics and Gynecology has just released a committee opinion to help providers structure preventive healthcare visits to screen for health issues and counsel patients about a variety of health topics, including reproductive health.
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Counsel women on how to cope with menopause’s vasomotor symptoms
New research indicates that frequent vasomotor symptoms associated with menopause could last more than seven years for many women.
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How to get the message across to young men about using condoms consistently and correctly
When used consistently and correctly, latex condoms are effective at preventing sexually transmitted infections, including HIV.
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Research eyes effect of body weight and BMI impact on emergency contraception
Results of a new statistical analysis of clinical data suggest a significant drop in the efficacy of levonorgestrel emergency contraceptive pills with increasing body weight.
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Intrauterine device and implant are effective beyond use approved by the FDA
An initial analysis of data conducted by Washington University School of Medicine in St. Louis indicates that hormonal intrauterine devices and contraceptive implants remain highly effective one year beyond their approved duration of use.