Clinical
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Can You Make ‘Flat’ Basal Insulin ‘Flatter?’
For patients incurring problematic episodes of hypoglycemia, an insulin that provides even “flatter” plasma levels may provide an advantage.
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FDA Actions
The FDA has approved two drugs for the treatment of diarrhea-predominant irritable bowel syndrome.
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Addition of Ezetimibe to Simvastatin May Improve CV Outcomes
A new study suggests the addition of ezetimibe to simvastatin may improve cardiovascular outcomes in patients with acute coronary syndrome, although the effect is modest.
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Beta-blockade Use in Non-cardiac Surgery Patients
Perioperative beta-blockade appears to be beneficial for patients with high cardiac risk factors undergoing NCS, but it increased the risk of death in those with no cardiac risk factors.
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ECG Review: Is There Complete AV Block or Any Block at All?
We summarize the five parameters to assess in the interpretation of any cardiac rhythm by the saying, “Watch your Ps and Qs — and the 3Rs.”
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Clinical Briefs
In this issue: Carbon monoxide toxicity in the elderly; Does hypovitaminosis D increase risk of atrial fibrillation in hypertensive patients?; and reflections on the consequences of morning BP surge.
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Liraglutide Injection (Saxenda®)
The glucagon-like peptide (GLP-1) receptor agonist, liraglutide is now approved for weight management in adults.
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Inpatient and Outpatient Care Providers: Why Can’t We Just Work Together?
The authors of this paper did a qualitative study to analyze the barriers and solutions to care coordination between hospitalists and primary care providers in North Carolina.
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Efficacy of Folic Acid Therapy in Primary Prevention of Stroke
Among adults with hypertension in China without a history of stroke or myocardial infarction, the combined use of enalapril and folic acid, compared with enalapril alone, significantly reduced the risk of first stroke.
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Drug-related HIV outbreak spurs CDC to issue nationwide alert
The CDC has issued a national health advisory in light of its investigation with the Indiana State Department of Health of a large outbreak of recent HIV infections among persons in Indiana who inject drugs.