Clinical
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Liraglutide Effective for Weight Loss in Diabetics
Among overweight and obese participants with type 2 diabetes, use of subcutaneous liraglutide daily compared with placebo resulted in weight loss over 56 weeks.
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Rosacea is Associated with Cardiovascular Disease
While the mechanism for the relationship between rosacea and cardiovascular disease is ill-defined at this point, one postulate is that systemic inflammation, which has been shown to alter the ability of lipoproteins to remove cholesterol from circulation, might be at least part of the explanation.
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Approaches to PTSD in Veterans
Mindfulness-based stress reduction shows promise as a valuable intervention for PTSD patients.
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Cardiovascular Autonomic Neuropathy Occurs Earlier in Type 2 Diabetes
Study results suggest cardiovascular autonomic neuropathy (CAN) may occur quite early, but whether treatment of diabetes might alter the course of CAN remains unknown.
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Early Identification, Intensive Intervention for Diabetes Might Improve Cardiovascular Outcomes
Multifactorial trials in which blood pressure, lipids, weight, exercise, and glucose are concomitantly addressed have produced favorable CV risk reduction, but it becomes difficult to ascertain which component(s) of the multipronged intervention is most responsible for the beneficial outcomes.
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Reversing Anticoagulant Effect of Dabigatran
A tool for reversal of novel oral anticoagulant effects may soon be available.
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Likelihood of Occult Cancer Causing Unprovoked Deep Venous Thrombosis
The likelihood of identifying occult cancer in patients with new unprovoked deep venous thrombosis is not meaningfully enhanced by performing extended screening.
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ECG Review: Is There Complete AV Block?
The simultaneously-recorded 3-lead rhythm strip in the figure was obtained from a 75-year-old woman who presented to the emergency department with syncope. She was diagnosed as being in complete (third-degree) AV block. Do you agree with this interpretation?
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Clinical Briefs
Treating symptomatic venous thromboembolism with warfarin; extending the window of anticoagulation after pulmonary embolus; and stroke accelerates long-term process of cognitive decline.
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Sacubitril and Valsartan Tablets (Entresto)
A new option for heart failure incorporates two drugs with different mechanisms of action.