Clinical
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Migraine and Cognitive Dysfunction
During an attack of migraine without aura, patients may experience transient cognitive impairment, with predominant involvement of verbal processing speed, learning, and memory, due to reversible cortical dysfunction.
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Is Low Testosterone Therapy Worth the Hype in the Elderly?
Testosterone replacement therapy showed no impact on subclinical atherosclerosis progression in recent study.
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SGLT2 Inhibitors: Now The Bad News
Sodium-glucose cotransporter-2 inhibitors are approved as adjunctive therapy for the treatment of patients with type 2 diabetes. This drug class has been also used off-label to improve glycemic control in patients with type 1 diabetes.
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Morcellation: Has it Improved Outcomes or Put Women at Risk?
Widespread concern over malignant tumor dissemination with morcellation threatens to undermine advances in minimally invasive gynecologic surgery that have benefited women. Before providers abandon this technique, they should put the risks and benefits in perspective.
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Can Cerebroplacental Ratio Predict Neonatal Mortality?
Recent articles show the cerebroplacental ratio to be a useful predictor of immediate and later neonatal morbidity, particularly, in late-onset intrauterine growth restriction.
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Quality of Information on Pelvic Organ Prolapse on the Internet
After review of more than 400 websites, most web-based information available to women regarding pelvic organ prolapse treatment is incomplete. The best-quality information was found on government-sponsored websites.
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Flibanserin: A Billion Dollar Market?
On the third attempt, the FDA approved the treatment for generalized hypoactive sexual desire disorder in premenopausal women.
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FDA Actions
In this section: Drug to treat hypoactive sexual desire disorder in premenopausal women goes live; new drug available to prevent delayed phase chemotherapy-induced nausea and vomiting; DPP-4 inhibitors used to treat type 2 diabetes may cause severe and disabling joint pain; and evolocumab receives approval.
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Aspirin and NSAIDs Reduce Colorectal Cancer Risk
Long-term continuous use of low-dose aspirin and long-term use of non-aspirin nonsteroidal anti-inflammatories was associated with reduced colorectal cancer risk.
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Chronic Sinusitis Recognized as Inflammatory Disease
Evidence supports daily high-volume saline irrigation along with topical corticosteroids as first-line therapy.