Clinical
RSSArticles
-
Direct-to-Consumer TV Ads Push Drugs of Scant Therapeutic Value
Many people assume TV ads for prescription drugs are for new, cutting-edge medications that represent groundbreaking advances. However, there is growing evidence suggesting otherwise.
-
Tool Identifies Patients in Need of Serious Illness Conversations
Text messages generated by a machine-learning tool resulted in clinicians engaging in more serious illness conversations with high-risk patients.
-
Bias and Stigma Hinder Effective Obesity Treatment
The industry is moving away from a hierarchy of care where a primary provider tells the patient what they ought to do. Instead, the model is moving toward shared decision-making.
-
CDC: Candida auris Spreading at ‘Alarming’ Rate
The agency reported the number of clinical cases has risen each year since 2016, with the worst spike occurring during the 2020-2021 period.
-
When the Aortic Annulus Is Small, Does TAVR Valve Type Matter?
In this propensity-matched analysis of transcatheter aortic valve replacement (TAVR) registry patients with small aortic annuli, the hemodynamic advantage of self-expanding TAVR valves was not associated with better clinical outcomes compared with balloon-expandable valves up to five years.
-
Does One Negative Troponin Measurement Rule Out Acute Coronary Syndrome?
Using a common clinical chest pain algorithm plus a point-of-care troponin measurement for low-risk patients, researchers reported significantly lower healthcare costs. Also, this approach did not seem to result in more major adverse cardiovascular events.
-
Bleeding Risk with Combination Amiodarone and Direct-Acting Oral Anticoagulants
Among patients with atrial fibrillation who were taking a direct-acting oral anticoagulant, there was a significant association between major bleeding and amiodarone use within 60 days, but no association with amiodarone use longer than 60 days before the bleed.
-
Unexpected Low Voltage on an ECG
A registry study of hypertrophic cardiomyopathy (HCM) patients and elite athletes in Italy revealed low voltage on ECG is not uncommon in HCM and may be a marker for more left ventricular scarring on cardiac imaging — and a poor prognosis.
-
Diagnosis of Myasthenia Gravis May Be Challenging
Mimics of myasthenia gravis, including functional neurologic disorder, progressive external ophthalmoplegia, chronic ptosis, oculopharyngeal muscular dystrophy, mitochondrial cytopathy, or low-grade myositis, can make the diagnosis of myasthenia gravis difficult.
-
Is the Long-Term Use of Low-Dose Opioids for the Treatment of Refractory RLS Safe and Effective?
A review of two-year longitudinal data regarding efficacy and dose stability in refractory restless legs syndrome (RLS) patients treated with low-dose opioids shows that patients do not escalate their opiate dosage and that there is clinical and therapeutic stability in the treatment of RLS with this therapeutic regimen. Methadone is the preferred opiate for the treatment of RLS because of its single-dose, long-acting profile and lack of euphoric effects.