Clinical
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Are We on the Threshold of a New Approach to Evaluating Women with Recurrent Pregnancy Loss?
A small retrospective cohort study raises the possibility that advanced genetic techniques can be used to analyze the products of conception in women with recurrent pregnancy loss to identify those most likely to have treatable reasons for their miscarriages.
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Induction of Labor in Patients with Previous Cesarean Sections
ABSTRACT & COMMENTARY: Great improvements have been made while the fear of litigation ebbs.
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ECG Review: A 43-Year-Old Man with Atypical Chest Pain
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Clinical Briefs
In this section: reversing the anticoagulant effect of dabigatran; considering the likelihood of occult cancer causing unprovoked deep venous thrombosis; and cardiovascular autonomic neuropathy occurs earlier in type 2 diabetes.
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Evolocumab Injection (Repatha)
Evolocumab is indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease in patients who require additional lowering of LDL-C.
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Vitamin D and Diabetic Neuropathy
Vitamin D deficiency may exacerbate the clinical manifestations of diabetic neuropathy, and supplementation with vitamin D3 may be beneficial.
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Nutrition Therapy for Hypertension Using the Nitric Oxide Pathway
Daily one-time ingestion of inorganic nitrate from beet juice consistently lowered blood pressure in hypertensive patients by an amount comparable to single-drug therapy.
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Intensification of Oral Therapy for Type 2 Diabetes
ABSTRACT & COMMENTARY: It may not be relevant to primary care physicians. Here's why.
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FDA Actions
FDA strengthens warning about canagliflozin, approves cariprazine to treat schizophrenia and bipolar disorder, and green lights insulin degludec, a new long-acting insulin analog.
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Spironolactone Effective Add-on for Resistant Hypertension Patients
Spironolactone was the most effective add-on drug for treatment of resistant hypertension, suggesting that sodium retention plays a role in this condition.