Clinical
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Tranexamic Acid-associated Seizures: Features, Mechanisms, and Treatment
Tranexamic acid is a commonly used antifibrinolytic drug that has been associated with increased risk of postoperative seizures. The authors reviewed the incidence, risk factors, and clinical features of these seizures, as well as potential mechanisms. They also proposed treatments and interventions for preventing Tranexamic acid-related seizures.
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Does Rivastigmine Prevent Falls in Parkinson’s Disease?
A randomized, double-blind, placebo-controlled Phase II clinical trial of oral rivastigmine in 130 patients with moderate-stage Parkinson’s disease demonstrated improved gait stability as measured by accelerometry, and suggested an association with lower rate of falls.
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Intraoperative Neurophysiologic Monitoring: Does it Change the Outcome from Spinal Surgery?
In non-complex spine surgeries (spinal decompression and spinal fusion), intraoperative neurophysiologic monitoring improved clinical outcomes and reduced the risk of neurological complications by nearly one-half (49%).
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Sonographic Diagnosis of Inclusion Body Myositis
Inclusion body myositis has remained a clinical diagnosis assisted by a muscle biopsy, but now muscle ultrasound and biomarker identification may aid diagnosis.
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Potatoes Increase Risk of Type 2 Diabetes Mellitus
Potato consumption, particularly in the form of French fries, is strongly correlated with the development of type 2 diabetes.
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Perils of High-dose Vitamin D Supplementation
Bischoff-Ferrari H, et al. Monthly high-dose vitamin D treatment for the prevention of functional decline. JAMA Intern Med 2016; doi:10.1001.
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Chinese Herbal Medicine for Esophageal Cancer
Although Chinese herbal medicine probably does not slow disease progression or improve survival in esophageal cancer patients, it may improve quality of life and reduce adverse effects of radiotherapy and chemotherapy.
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That’s Not a Hot Flash, It’s Kidney Yin Deficiency: Try Acupuncture?
Both real and sham acupuncture provide benefits for women suffering from menopausal hot flashes, including for months after the treatment ends.
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Chiropractic for Ankle Sprains
Ankle joint chiropractic manipulation as adjunctive therapy to typical rehabilitation improves symptoms of chronic ankle instability from repeated sprains.
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Fried Foods: Friend or Foe?
Frequent consumption of food fried (four or more times a week) in reused oils significantly increases obesity and type 2 diabetes, hypertension, and hyperlipidemia, and is associated with increased risk of cardiovascular disease. What remains unknown, however, is the ideal duration, temperature, and method for safe frying, as well as how often oil can be reasonably reused.