Clinical
RSSArticles
-
Optimal Antiplatelet Therapy for Secondary Prevention of Ischemic Stroke
Patients presenting with acute ischemic stroke are often taking aspirin on a regular basis for prevention of cardiovascular disease. The optimal antiplatelet therapy for secondary prevention has been uncertain in this setting.
-
Use of CNMs and Hospitalists
SYNOPSIS: A study assessing the effects of instituting a model of certified nurse midwife with MD laborist backup on a private patient population showed a decrease in cesarean section rate and an increase in vaginal birth after cesarean delivery rate without any change in combined neonatal outcome.
-
Prognostic Value of Coronary Calcium on Standard Chest CT Scans
SYNOPSIS: Coronary calcium scan on standard CT scans performed for other indications is of equivalent prognostic value to that seen on ECG-gated coronary studies and should be included in radiology test reports.
-
The Current Outlook for Cardiac Tamponade
SYNOPSIS: In the modern era, cardiac tamponade is most commonly caused by malignancies with poor prognosis. As compared to older literature, iatrogenic causes have increased, most resulting from complications of percutaneous coronary intervention.
-
The Best Rate Control Agent for Sepsis and Atrial Fibrillation
Sepsis and atrial fibrillation are common in the ICU, and the presence of both together is not a rare occurrence. Here's how to handle them.
-
Leigh Syndrome: Insights and Implications from Advances in Next-generation Sequencing
Leigh syndrome is a genetically heterogeneous neurodevelopmental disorder. The application of next-generation sequencing has enabled a deeper understanding of the diverse nature of the genetic and molecular etiologies that give rise to the shared clinical phenotype of Leigh syndrome.
-
Differentiating Sarcoidosis from Neuromyelitis Optic in Patients with Transverse Myelitis
Based on a retrospective analysis of 71 patients with an neuromyelitis optica spectrum disorder (n = 37) or sarcoidosis (n = 34), whose initial presentation was longitudinally extensive transverse myelitis (≥ 3 vertebral segments), the authors report clinical, radiologic, and laboratory findings that help distinguish one from the other.
-
Carpal Tunnel Syndrome: Everything You Want To Know, and More
Carpal tunnel syndrome can be reliably diagnosed, only with nerve conduction studies, and this test should be performed before any invasive treatments are initiated.
-
Relationship Between Spikes and Seizures Using an Implantable Intracranial Detection Device
The authors report the preliminary findings for an implantable ambulatory intracranial recording device for seizure detection in 15 subjects. One of the primary findings was that spike rate significantly changed prior to seizures in nine of 15 subjects. Six of these subjects showed a significant decrease in spiking prior to ictal onset, whereas the remaining three showed a significant increase in spiking and these three subjects had the best seizure prediction results.
-
Clinical Characterization of Inherited Erythromelalgia Due to Sodium Channel Mutations
A detailed non-interventional clinical study of patients with inherited erythromelalgia who carry gain-of-function mutations of voltage-gated sodium channel Nav1.7 further characterized pain phenotypes in this disorder and showed wide variability of pain symptoms.