Clinical
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Tarlov Cysts of the Lumbosacral Spine
Tarlov cysts (root sleeve cysts) are common incidental findings on magnetic resonance imaging of the lumbosacral spine. However, they rarely are correlated with electrophysiological findings or clinical symptoms. Undertake extreme care and caution before recommending surgical intervention for these common imaging abnormalities.
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Cumulative Number of Head Strikes Contributes to the Development of Chronic Traumatic Encephalopathy
Researchers recently evaluated the connection between head impact and chronic traumatic encephalopathy (CTE) in male athletes. They found the total number and severity of head impacts throughout life better predicted CTE than the number of symptomatic concussions.
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Super-Refractory Status Epilepticus: Clinical Characteristics, Treatment, and Outcome
Patients with super-refractory status epilepticus (SRSE) differed from patients with first-time status epilepticus in clinical presentations and the treatment course. Although seizure control was achieved in most SRSE patients, the in-hospital mortality and the chance of severe disability at discharge were high.
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Treatment of Preclinical Alzheimer’s Disease
After a four-year, complex clinical trial of an anti-amyloid antibody, solanezumab, there was no benefit in reducing the likelihood of progression of cognitive impairment in patients with positive amyloid positron emission tomography scans who started the trial cognitively unimpaired vs. placebo.
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Differentiating MELAS from Bland Ischemic Stroke: Clinicoradiologic Criteria
Stroke symptoms in mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) are difficult to diagnose correctly, which leads to missed opportunities to provide MELAS-specific treatment. Delay in diagnosis also complicates efforts to investigate acute treatments for MELAS. Khasminsky et al proposed clinicoradiologic criteria based on a single-center validation study. Although there are methodological limitations, the concepts highlighted by the authors are valuable.
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The Importance of Diagnosing Obstructive Sleep Apnea During Pregnancy
Obstructive sleep apnea is associated with several adverse maternal and fetal outcomes.
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Comparing the Effects of Electroacupuncture and Auricular Acupuncture on Pain Control?
This randomized clinical trial involves 360 cancer survivors and found that two types of acupuncture demonstrated superior pain control compared to usual care during a 12-week follow-up period.
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Endometriosis and the Gut Microbiome: Nutritional Prospects in the Treatment of a Chronic Disease
Endometriosis is characterized by the presence of endometrial glands and stroma in any extrauterine site, such as the ovary, fallopian tubes, pelvic peritoneum, rectovaginal space, bowel, and, rarely, lungs and brain. Standard treatment of endometriosis may involve the use of pain relievers such as nonsteroidal anti-inflammatory drugs, hormonal therapy and modulators, and/or surgical removal of endometriotic tissue. On average, women seek consultation from three different healthcare providers over several years to receive a diagnosis of endometriosis. The delay in care results in significant long-term morbidity.
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Patient Advocates Launch National Diabetes Treatment Recognition Program
Hospitals can be evaluated based on their care for patients with diabetes during admission, stay, and discharge.
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Incident Dementia Cases Connected to Long-Term Air Pollution Exposure
Researchers reported fine particulate matter from agriculture and open fires to be especially harmful.