Clinical
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Good News for Type 2 Diabetics
The rate of the first occurrence of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke among patients with type 2 diabetes mellitus was lower with liraglutide than with placebo.
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Drug May Slow Renal Disease Progression
In patients with type 2 diabetes at high cardiovascular risk, empagliflozin was associated with slower progression of kidney disease and lower rates of clinically relevant renal events than was placebo when added to standard care.
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Safe, Effective Alternatives to Warfarin
Non-vitamin K antagonist oral anticoagulants are safe and effective alternatives to warfarin in the routine care setting.
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CDC Advisory Committee Recommends Against Live Attenuated Influenza Vaccine
The decision came after a committee reviewed data showing vaccine effectiveness for the live attenuated influenza vaccine of only 3%.
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Cocaine Use and Pyoderma Gangrenosum
In addition to the other obvious concerns about cocaine use, add pyoderma gangrenosum to the list.
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Considering Perioperative Statins in Cardiac Surgery
Despite early data suggesting benefits of perioperative statin treatment, a larger data set fails to confirm benefit and indicates some potential harm.
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Vindication of Salmeterol-Fluticasone Single-inhaler Combination
The prescription of long-acting beta agonists monotherapy for asthma patients is still appropriate, but data are reassuring in regard to long-acting beta agonists + fluticasone therapy.
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Chronic Fatigue Syndrome and Serious Adverse Outcomes
The marked increased risk for suicide in chronic fatigue syndrome patients suggests clinicians should enhance their vigilance for chronic fatigue syndrome and promptly intervene with patients who screen positive for depression.
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Who Should Receive Diabetes/Prediabetes Screening?
Although treating patients with prediabetes delays progression to diabetes, it remains to be seen whether such early identification actually reduces clinical events.
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A Newly Identified Statin Toxicity
Most cases of statin-associated autoimmune myopathy treated in a timely fashion with immunosuppressive therapy produce favorable outcomes.