Clinical
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The Effect of Major Depression on Quality of Life After Surgery for Stress Urinary Incontinence
Women with major depression undergoing surgical treatment for stress urinary incontinence have worse condition-specific quality of life than non-depressed women. Postoperatively, depressed and non-depressed women have similar incontinence severity and quality of life.
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The Best Medical Treatment for Endometriosis? The Debate Continues
In a “before and after study,” the proportion of satisfied and very satisfied women did not change from the “before” period, during which women with endometriosis were treated with norethindrone acetate, to the “after” period during treatment with dienogest.
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FDA Actions
Agency approves prasterone to treat women with moderate to severe dyspareunia due to menopause-related vulvar and vaginal atrophy.
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Notable COX-2 Inhibitor Carries Same CV Risks as Traditional NSAIDs
However, promising report not without its critics.
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Exploring Therapies to Reduce Pelvic and Hip Fractures
More evidence suggests thiazides improve bone strength and reduce fracture risk by exerting a positive effect on calcium balance and perhaps a direct stimulatory effect on osteoblasts.
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PPI Use and Community-acquired Pneumonia Risks
A new study concluded that the previously noted association between proton pump inhibitor use and community-acquired pneumonia is “likely to be due entirely to confounding factors.”
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High-dose Statins as a Secondary Prevention
Researchers found there was a graded association between intensity of statin therapy and mortality in patients suffering from atherosclerotic cardiovascular disease.
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USPSTF Updates Guideline on Screening for Lipid Disorders in Adults
New guideline recommends low- to moderate-dose statins in adults 40-75 years of age without a history of cardiovascular disease who present with one or more risk factors and a calculated 10-year cardiovascular disease event risk of ≥ 10%.
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An Alternating QRS with AV Block?
There is no 12-lead ECG on this patient, which means that our assessment of QRS morphology is limited to this single right-sided MCL-1 monitoring lead.
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Clinical Briefs
In this section: connecting asthma to obesity; finding the right treatment for uncomplicated gastroesophageal reflux disease; and better blood pressure control.