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  • Diastolic Blood Pressure Goals

    An analysis of the community-based ARIC study showed that low diastolic blood pressures were associated with higher baseline and subsequent troponin T levels and adverse cardiac events, but not stroke.

  • Male Hypogonadism

    Testosterone replacement therapy is a growing industry that deserves discussion between patients and their healthcare providers. Recently, many insights into new formulations, advertising, and potential risks have heightened the controversy surrounding low testosterone syndrome, appropriate diagnosis, and risks and benefits of testosterone supplementation. A plethora of non-regulated supplements termed “testosterone boosters” are being marketed directly to the public without adequate assessment. Therefore, it is important for healthcare providers to be familiar with how to conduct and interpret diagnostic tests as well as with appropriate use of TRT as established by various medical organizations, including the Endocrine Society. This review will discuss the definitions, pathophysiology, causes, clinical manifestations, appropriate diagnostic testing procedures, and the role of testosterone supplementation with currently available formulations, with special attention to efficacy and adverse effects in hypogonadism in men.

  • Dietary Supplement Trends, 1999-2012

    The authors reported that approximately 25% of supplement use had been recommended by a healthcare provider.

  • New Tools for Glucose Monitoring

    Does the FreeStyle Libre outperform traditional fingerstick methodologies?

  • Placebo for Osteoarthritis Pain

    Positive placebo response from patients occurs most fruitfully when patients feel safe, calm, and validated by their clinician.

  • Are We Using Novel Oral Anticoagulants Wisely?

    Researchers retrospectively analyzed data from 224 patients who had been prescribed reduced-dose novel oral anticoagulants to determine if the dose reductions had been according to appropriate indications (as per labeling) as well as appropriate in amount of dose reduction.
  • Lung Cancer Screening at a VA Medical Center

    It is incumbent on clinicians to offer screening to appropriately selected patients.

  • Topical Agent for Premature Ejaculation

    Promescent was effective in prolonging time to ejaculation, and was well tolerated.

  • Extending Life of LARCs: More Years for Your Implant

    An international study found that continued use of an etonogestrel contraceptive implant for up to five years, two years longer than the current labeling approval, did not increase the risk of pregnancy.

  • When to Start Progestin-only Contraceptives After Medical Abortion

    In this randomized, controlled trial, provision of depot medroxyprogesterone acetate on the same day as mifepristone for medical abortion decreased efficacy a small amount and had no effect on repeat pregnancy at six months. Whether this is clinically relevant will depend on individual patient counseling and the woman’s desire for convenient contraceptive coverage.