Clinical
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Promising Treatment for Multiple Sclerosis Closer to Approval
Ocrelizumab may be closer to approval for the treatment of progressive multiple sclerosis based on the recently published results of two studies.
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Comparing First-line Treatments for C. difficile Infections
Vancomycin and metronidazole are both used as first-line treatment for C. difficile infections, but vancomycin may be superior in reducing 30-day mortality.
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Approved Drug Demonstrates Efficacy in Battling Potent Bacterial Infection
Bezlotoxumab was associated with a substantially lower rate of recurrent C. difficile infection compared to placebo with a good safety profile.
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Class Action Suit Accuses Pharmaceuticals of Fixing Prices
A class action lawsuit accuses insulin manufacturers of fixing prices and conspiring to increase the cost of their essential medication.
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New Report Raises Red Flags About Antiviral Agents and the Possibility of Liver Failure
The Institute for Safe Medication Practices reported on 524 cases of liver failure in the past 12 months associated with direct-acting antiviral agents for treating hepatitis C.
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A Melodious Path to Addressing Dementia Issues
Clinicians might consider informing involved family members or caretakers of the potential positive effects of music therapy.
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The Way to a Man’s Heart Is Through His Stomach?
Although the aphorism “the way to a man’s heart is through his stomach” may have been intended to reflect another agenda, it may turn out to be far more true than most of us expected.
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Cardiovascular Risk Induced by NSAIDs
The most recent American College of Cardiology/American Heart Association guidelines on acute coronary syndromes place nonsteroidal anti-inflammatory drugs at the bottom of the list of choices to treat musculoskeletal pain.
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Comparing Treatments for Peripheral Artery Disease Patients
The success that ticagrelor has achieved in acute coronary syndromes prompted the question of whether ticagrelor might provide greater reduction in cardiovascular events than clopidogrel.
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The Dubious Benefits of Urinalysis in Asymptomatic Patients
Both the Infectious Diseases Society of America and the American Board of Internal Medicine advise against treatment of asymptomatic bacteriuria in non-pregnant adults.