Clinical
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Embryo Implantation
A recent study tracking embryos after embryo transfer has provided insight into why embryos have a greater tendency to ultimately implant in the lower uterine segment, thereby predisposing patients to a greater risk of placental complications.
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Contraception, Migraines, and Stroke
In this case-control study, women with migraines with aura using combined hormonal contraception had six times the odds of experiencing ischemic stroke compared to women without migraines not using combined hormonal contraception. Use of combined hormonal contraception among women with migraines without aura was not associated with an increased risk of stroke over baseline.
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Hate Traffic? You Might Be Forgetting Something
As clinicians search for remediable explanations for Alzheimer’s disease and other dementias, several epidemiologically intriguing potential culprits have emerged, including air pollution and diesel exhaust.
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Sickle Cell Trait Falsely Lowers Hemoglobin A1c
Clinicians may wish to include additional diagnostic tests for diabetes in persons with sickle cell trait, such as fasting glucose, postprandial glucose, or oral glucose tolerance testing.
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Atopic Dermatitis Associated With Autoimmune Disorders
The list of autoimmune disorders linked with atopic dermatitis has expanded to include vitiligo, alopecia, lupus, and inflammatory bowel disease.
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Antisocial Behavioral Syndromes in the United States
Whether treatment for the numerous other comorbidities, such as substance abuse associated with antisocial personality disorder, will hasten time to remission is an area of needed research.
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Preventing Sickle Cell Disease Pain Crises
Crizanlizumab has been demonstrated to be highly effective in reducing painful crises related to sickle cell disease.
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Recognizing Binge Eating Disorder
Because binge eating disorder is more common in persons with obesity, screening potentially is more useful in this population.
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FDA Action
The FDA has approved brodalumab to treat adults with moderate-to-severe plaque psoriasis.
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A Possible New Hope for Leukemia Patients
Treatment with blinatumomab resulted in significantly longer overall survival than chemotherapy among adult patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia.