Clinical
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Breast Cancer Screening Recommendations Amid Changing Guidelines
A recently published research letter contains in-depth information about breast cancer screening recommendations physicians give their patients amid recent guideline changes.
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New U.S. Zika Figures Prompt Healthcare Providers to Play a Key Role in Prevention Efforts
Although it has been more than a year since the CDC released the first travel alert related to Zika virus in the Americas, experts warn now is not the time to be complacent.
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Diabetes Microvascular Complications
Diabetes mellitus is expensive, but most of the costs are attributed to complications and hospital care. This article will review the recommendations from the ADA 2017 Standards of Care for microvascular complications and relevant position statements, and will highlight preventive screening and clinical pearls for the primary care physician treating patients with diabetes.
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A Novel Target for Migraine Prevention Through Modulation of Stress Receptors
Kappa opioid receptors (KORs) modulate response to stress, a common migraine trigger, so KOR blockade may be a novel preventive treatment for migraine as well as other stress-related diseases.
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Outcomes After Surgical Treatment of Nonlesional Neocortical Epilepsy
In this study of 109 consecutive patients with medically refractory neocortical epilepsy without MRI-identifiable lesions who underwent focal resection at a single hospital from 1995 to 2005, almost 60% of patients achieved long-term seizure freedom, with anti-epileptic drugs being withdrawn successfully in about a third of these patients.
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Bright-light Therapy for Daytime Sleepiness in Parkinson’s Disease Patients
Light therapy has been shown to be beneficial in treating excessive daytime sleepiness in Parkinson’s disease patients and also may improve sleep quality.
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Fludrocortisone for Orthostatic Hypotension Associated With Parkinson’s Disease
This double-center, double-blind, randomized, controlled trial compared the efficacy of pyridostigmine bromide vs. fludrocortisone and demonstrated that pyridostigmine bromide was not as effective as fludrocortisone. The authors also provided evidence for the efficacy of fludrocortisone in treating neurogenic orthostatic hypotension.
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Rituximab for Myasthenia Gravis
In uncontrolled, observational case series, rituximab treatment for myasthenia gravis appears to be effective and safe, but more studies are needed for confirmation.
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Blood-brain Barrier Breakdown in RCVS
In this single-center, prospective trial, patients with reversible cerebral vasoconstriction were found to have evidence of blood-brain barrier breakdown on MRI.
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Beetroot Juice and Aerobic Endurance and Blood Pressure
Researchers found that drinking beetroot juice daily improves submaximal aerobic endurance in patients with cardiac failure and preserved ejection fraction.