Clinical
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Association of Autism with Antidepressant Use During Pregnancy
Two new studies suggest that maternal use of antidepressants during pregnancy is not associated with autism.
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PCSK9 Drug Improves Heart Outcomes
Although evolocumab and alirocumab lowered low-density lipoprotein better than statins, evidence of cardiovascular benefit had been lacking — until now.
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Exercise-induced Rhabdomyolysis
Patients who decide to choose spinning (cycling) as their exercise method must be cautioned to build exercise intensity gradually.
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Efficacy of Mandibular Advancement Devices vs. CPAP
Authors a recent paper recommended that continuous positive airway pressure should remain the first-line treatment for most patients, perhaps because the studies employing mandibular advancement devices have been restricted to less severe obstructive sleep apnea cases.
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Cardiovascular Consequences of Weight Gain
Clinicians should be vigilant to offer patients with coronary disease advice about optimal weight management.
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Liraglutide for Prevention of Diabetes
Liraglutide is the newest agent to be added to the list of successful agents for combating diabetes.
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Surgical Replacement: Younger vs. Older Knees and Hips
Data suggest that clinicians inform potential subjects of the greater likelihood for repeat surgery if initial replacement surgery is performed on patients < 70 years of age.
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Spinal Manipulation for Low Back Pain
Whether the degree of pain reduction attributed to spinal manipulation therapy reported here will satisfy many clinicians is questionable.
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Is This Fascicular Ventricular Tachycardia?
The ECG in the figure in this story was obtained from a 55-year-old man who presented for emergency care with palpitations and fatigue. His blood pressure was 80/50 mmHg at the time the tracing was recorded. Is this a case of ventricular tachycardia?
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Clinical Briefs
In this section: treating depression; the subdural risk of antithrombotics; and the health consequences of a poor diet.