Clinical
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Clinical Briefs
In this section: Use caution with a nocturia treatment; an analysis of a cellulitis remedy; and handling influenza patients.
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Sarilumab Injection (Kevzara)
Sarilumab is indicated for the treatment of adults with moderately to severely active rheumatoid arthritis who have demonstrated an inadequate response or intolerance to one or more disease-modifying antirheumatic drugs.
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Possible Benefit From Pharmaceutical-grade Chondroitin on Knee Osteoarthritis
The authors of a European study found a statistically significant and clinically marginally significant reduction in pain at three and six months in patients taking pharmaceutical-grade chondroitin sulfate for knee osteoarthritis.
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Glucose Self-monitoring May Not Be That Useful
Researchers could not find any statistically significant differences in glycemic control or health-related quality of life between patients who performed glucose self-monitoring compared with those who did not.
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Early Hot Flashes Could Signal Increased Risk for Heart Disease
Women 42-55 years of age who experience hot flashes are more likely to exhibit poor vascular function.
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FDA Actions
In this section: New FDA commissioner off to fast start on opioids, drug safety, and orphan drug designation.
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Comparing Insulin Treatments for Diabetic Patients
Authors of two studies suggested that 32 weeks’ treatment with insulin degludec vs. insulin glargine U100 resulted in a reduced rate of overall symptomatic hypoglycemic episodes.
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Exploring the Rising Prices of Generic Drugs
Study: As competition among generic drugs decreases, prices go up.
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Investigators Tackle Antimicrobial Resistance
Researchers suggested that “modified use of antimicrobial agents and public health interventions, coupled with novel antimicrobial strategies, may help mitigate the effect of multidrug-resistant organisms in the future.”
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Antibiotics for Upper Respiratory Infections in Elderly Patients
Physicians who were more likely to prescribe an antibiotic for an acute upper respiratory tract infection included mid- and late-career physicians, physicians trained outside of Canada or the United States, and high-volume physicians.