Clinical
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More Teens Using Contraception, Data Show
While more relying on IUDs and other methods, pill use remains common
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Fungus Among Us? Dermatophyte Infections, Mimickers, and Treatment Options
Tinea refers to a superficial fungal infection of the skin, hair, and nails caused by dermatophytes, which are filamentous fungi. Trichophyton rubrum is the most common cause of dermatophyte infection, accounting for nearly 70% of infections worldwide. These infections are extremely common, but are more prominent in warm, tropical climates. Tinea is seen more commonly in black and Asian patients, has a predilection for young adults, and is three to four times more common in males.
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Infectious Disease Alert Updates
How Dirty Is That Sandbox?; Rebuilding the Pyramids; Resistant TB in India: Unrecognized Mutations
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GASP! Increasing Worldwide Antibiotic Resistance in Neisseria gonorrhoeae
Antibiotic-resistant gonorrhea threatens to make the infection untreatable in some patients.
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Genital HPV in Men: How Common Is It?
In this U.S. cross-sectional survey, the prevalence of genital human papillomavirus (HPV) infection in adult men was 45%, of which 25% were high-risk subtypes. The overall rate of HPV vaccination among those who were eligible was 11%.
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Azithromycin for Chronic Persistent Asthma
Azithromycin reduced exacerbations and improved quality of life in patients with chronic persistent asthma.
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Tetracycline for Multiple Sclerosis?
One hundred forty-two patients within 180 days of their first demyelinating event were randomized to minocycline 100 mg BID vs. placebo. The unadjusted risk of conversion to multiple sclerosis within six months after randomization was 61.0% in the placebo group and 33.4% in the minocycline group. At 24 months, the effect of minocycline was not statistically significant.
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Cefazolin Leads to Better Outcomes for Methicillin-susceptible Staphylococcus aureus Bacteremia Than Nafcillin or Oxacillin
A retrospective study that included patients from 119 Veterans Affairs hospitals found lower mortality and a similar recurrence rate for methicillin-susceptible Staphylococcus aureus bacteremia treated with cefazolin compared to nafcillin and oxacillin.
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Neonatal Group B Streptococcal Bacteremia Associated With Placentophagy
Associated with a mother’s ingestion of encapsulated placenta, an otherwise healthy newborn developed and, with antimicrobial treatment, recovered from both early and late onset group B streptococcal bacteremia. This is apparently the first report of a serious negative consequence of maternal consumption of dried placenta.
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Prevalence of Coronary Atherosclerosis in Indigenous South American Tsimané
Tsimané, a population living in the Bolivian Amazon, have the lowest prevalence of coronary artery disease among any population studied; individuals ≥ 40 years of age have mean low-density lipoprotein and high-density lipoprotein of 91 mg/dL and 39.5 mg/dL, respectively, despite a high inflammatory burden from parasites and pathogens.