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Infections Associated With Adventure Travel
Some adventure travel is associated with exposure to infectious pathogens. Some adventure-related illnesses can be prevented. Understanding the details of an adventure trip can help focus a differential diagnosis for ill returned travelers.
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Mild Traumatic Brain Injury Induces Altered Sleep and Impaired Memory
Traumatic brain injury may induce a chronic state of altered sleep with impaired memory consolidation and mood disorders.
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Autochthonous Crimean-Congo Hemorrhagic Fever in Europe
Two patients with Crimean-Congo hemorrhagic fever acquired in Spain are reported. The index patient acquired infection from a tick bite, and the second patient was a nurse who cared for the index patient. The first patient died in the hospital with multi-system organ failure and was diagnosed at autopsy. The second patient recovered with supportive care and was treated with ribavirin, but it was unclear whether the use of ribavirin was helpful.
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Microbiology of Hidradenitis Suppurativa: New Evidence That Anaerobes Predominate
Using metagenomic techniques, investigators determined that two Gram-negative anaerobes, Prevotella and Porphyromonas, predominate in hidradenitis suppurativa lesions. Two others, Fusobacterium and Parvimonas, correlate with disease severity.
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CDC Update of Notifiable Infectious Diseases
CDC has updated the available information regarding reportable infectious diseases in the United States.
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Does Celecoxib Pose Greater Cardiovascular Risks Than NSAIDs?
A controlled trial that included patients with arthritis on nonsteroidal anti-inflammatory drug (NSAID) therapy who were randomized to continuing NSAIDs or switching to celecoxib showed that cardiovascular and gastrointestinal event rates are low and not different on the two therapies.
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Palliative Care-based Intervention Improves Quality of Life in Chronic Heart Failure
Among patients with advanced heart failure, implementation of an interdisciplinary palliative care intervention was associated with improved quality of life.
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Frailty as a Patient Assessment Tool Prior to Aortic Valve Replacement
Assessment of frailty adds important prognostic information about risk of death and disability following both surgical aortic valve replacement and transcatheter aortic valve replacement.
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Percutaneous Coronary Interventions in Nonagenarians
Nonagenarians can undergo percutaneous coronary interventions with low in-lab complication rates, but 30-day and one-year mortality is considerably higher than in younger patients.
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How Much Might the Ejection Fraction Improve? Predicting Response to Premature Ventricular Complex Ablation
Several echocardiographic and electrocardiographic features were identified that can help predict if a cardiomyopathy is caused purely by frequent premature ventricular complexes and whether left ventricular function will normalize with ablative therapy.