Clinical
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Sofosbuvir, Velpatasvir, and Voxilaprevir Tablets (Vosevi)
Vosevi is indicated for the treatment of adult patients with chronic hepatitis C infection without cirrhosis or with compensated cirrhosis who are infected with genotype 1, 2, 3, 4, 5, or 6, and have been treated previously with a hepatitis C regimen containing an NS5A inhibitor.
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Eat Right, and Live
An improvement in diet over 12 years in middle-aged nurses and other health professionals resulted in a decreased risk of death.
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Glucose Self-monitoring Not Helpful for Non-insulin-treated Type 2 Diabetes
In this pragmatic randomized trial, self-monitoring blood glucose did not lead to lower hemoglobin A1c levels or improvement in health-related quality-of-life measures.
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Contraceptive Research: Science Heads to New Frontiers
Funding recently has been awarded to scientists around the globe through the Grand Challenges Explorations program, an initiative funded by the Bill & Melinda Gates Foundation. The program seeks to foster concepts for contraceptive discovery platforms that can contribute to the development of new methods suitable for women and men living in limited resource settings.
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Increased Focus on Preventing Preeclampsia
Cases of preeclampsia in the United States have increased since 1980 from 2.4% of all pregnancies to 3.8% in 2010. This increase is cause for concern: Preeclampsia accounts for more than $2.18 billion of the healthcare expenditure in the first 12 months after birth.
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‘Talk. Test. Treat.’ Aimed at Syphilis
There are more reported cases of primary and secondary syphilis in the United States now than there have been in more than 20 years. The Centers for Disease Control and Prevention has issued a call to action to reverse the trend.
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Task Force Issues Draft Guidance on Ovarian Screening
The U.S. Preventive Services Task Force has issued a draft recommendation statement on ovarian screening, finding that the potential harms of screening outweigh the benefits.
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Vasectomy Poses Minimal Prostate Cancer Risk
A new systematic review and meta-analysis of three decades of evidence concludes that vasectomies are associated with minimal risk of prostate cancer.
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Research Finds Many Women Who Receive IUD for Emergency Contraception Continue Use
Sixty-seven percent of women offered long-acting option were using it at one year.
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Value-based Payments and Primary Care
Over the past two decades, Medicare and commercial payers have increasing linked healthcare payments to quality. These new payment models are broadly referred to as value-based, as payers primarily focus on clinical and financial outcomes of patients rather than simply paying for services in an unsustainable fee-for-service model. This shift provides a unique opportunity for primary care to recapture its place in healthcare delivery as the original advocate for patient-centered care and the center of value. Primary care clinicians can be rewarded with additional revenue for creating efficient care delivery by developing the skill sets to manage value-based care.