Clinical
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Late Mortality With Paclitaxel-Coated Balloons and Stents in Peripheral Arterial Disease
A newly published meta-analysis of randomized, controlled trials concerning paclitaxel-coated balloons and stents in femoral popliteal disease patients revealed a marked increase in all-cause death at two and five years.
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Pregnancy Temporarily Increases Breast Cancer Risk: Parallels to Hormonal Contraception?
In a pooled analysis of prospective studies, researchers found an increased risk of breast cancer among parous women that persists for more than 20 years after childbirth. Breastfeeding did not modify this pattern.
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Low-Dose Aspirin and Preterm Birth
SYNOPSIS: A reanalysis of an earlier randomized clinical trial to assess the ability of low-dose aspirin to prevent preeclampsia has shown that the drug diminishes the risk of spontaneously delivering prior to 34 weeks by about half.
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Does Treatment of Bacterial Vaginosis Prevent Spontaneous Preterm Birth?
In this randomized, controlled trial from France, screening for and treatment of bacterial vaginosis in pregnant women at low risk for preterm birth with oral clindamycin or placebo did not reduce the rate of spontaneous preterm birth between 16 and 36 weeks.
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Paternal Age Is Important for Perinatal Outcomes
Fathering infants at or after age 45 years is associated with negative effects on both the mothers and the resulting offspring.
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A ‘Detective’ Diagnosis
The ECG in the figure was obtained from a 40-year-old man. Without the benefit of any history, how might one interpret this tracing? Is there evidence of an acute coronary syndrome? Is there a common diagnosis that potentially explains all the findings?
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Rifamycin Delayed-Release Tablets (Aemcolo)
Rifamycin is indicated for the treatment of traveler's diarrhea caused by noninvasive strains of Escherichia coli in adults.
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Patients Need to Rethink the ‘Quality’ in Healthcare
Increasingly, patient satisfaction is an important and commonly used surrogate marker for healthcare quality. Further, reimbursement to physicians may be based on patient satisfaction as a “quality” metric. But the evidence linking a patient’s subjective sense of satisfaction and the actual delivery of quality care remains tenuous.
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Healthcare-Associated Infections: Better, But Not There Yet
One-day prevalence studies demonstrated that there was a 16% reduction in the risk of healthcare-associated infections from 2011 to 2015.
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Factors Associated With Urinary Tract Infections Caused by Multidrug-Resistant Gram-Negative Bacteria
The authors of a multicenter, retrospective, cohort study from southern and eastern Europe identified predictive factors for multidrug-resistant complicated urinary tract infections.