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Infectious Disease Alert Updates
Imagine: Multidrug-Resistant GC; A New Borrelia Species in the ‘Old World’
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Baloxavir Marboxil (Xofluza)
Baloxavir marboxil is a novel, oral, antiviral agent approved by the Food and Drug Administration (FDA) on Oct. 24, 2018, for the treatment of acute uncomplicated influenza in patients 12 years of age and older.
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Staphylococcus aureus on the Playground and in the Gym — Is It Inescapable?
Staphylococcus aureus, including methicillin-resistant S. aureus, is a frequent surface environmental contaminant on both children’s playgrounds and in adult fitness centers.
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Adenovirus and CNS Disease in Children
Forty-eight immunocompetent children with adenovirus-associated central nervous system disease were described. Thirty-eight percent of patients died or experienced permanent neurologic sequelae.
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Sleep Tight, Don’t Let the Mucorales Bite
Mucorales were found to commonly contaminate linen delivered to 15 transplant and cancer centers in the United States.
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The Slippery Slope of Inappropriate Antibiotic Use in Children
Inappropriate antibiotic use for a child with a viral respiratory infection is not a “one and done” error. Children who receive antibiotics when diagnosed with a viral respiratory infection are more likely to seek care for viral infections subsequently and to receive inappropriate antibiotics again.
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Probiotics Do Not Prevent C. difficile Infection in Hospitalized Patients
A retrospective cohort study from a single California hospital found the administration of probiotics to patients receiving antibiotics did not reduce the incidence of healthcare facility-onset Clostridioides difficile infection.
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Are the Changes Acute?
Imagine the ECG in the figure was obtained from a previously healthy, middle-aged man who presented to an ambulatory clinic for “indigestion.” How might one interpret the ECG?
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Caplacizumab-yhdp for Injection (Cablivi)
Caplacizumab-yhdp is indicated for the treatment of acquired thrombotic thrombocytopenic purpura in combination with plasma exchange and immunosuppressive therapy.
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Homeless Population Requires Hepatitis A Vaccination
A multistate outbreak of hepatitis A virus (HAV) infection in the homeless and/or drug-using population has prompted the United States Advisory Committee on Immunization Practices to add “homelessness” as an indication for HAV vaccination. This is in addition to existing indications for HAV vaccination of men who have sex with men and illicit drug users (with the exception of marijuana use).