Clinical
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Year-Long Supply of Pills Effective in Preventing Pregnancy, Cutting Costs
Findings from the new paper, published by researchers at the University of Pittsburgh and the U.S. Department of Veterans Affairs, indicate that reducing birth control refills would be more effective for preventing undesired pregnancies among female veterans. The money saved on healthcare costs would more than outweigh the expense of providing multiple pill packs at one time.
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Revamping the Daily Pill: Research to Begin on Monthly Pill
Although lowering side effects plays an important role in oral contraceptive compliance, one of the biggest challenges for patients is adhering to the daily schedule of the pill. Forgetting one to three pills per cycle is a frequent problem among 15-51% of users, particularly among adolescents. Lyndra Therapeutics has received a $13 million grant from the Bill & Melinda Gates Foundation and is setting out to remove the daily pill compliance challenge. The company is in early development of a monthly oral contraceptive to provide women with a discreet, noninvasive, reversible contraception option.
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Poor Diet May Cause More Than 80,000 Cancers Each Year in the United States
In a recent analysis, investigators noted a correlation between a diet loaded with processed red meat and various types of cancers.
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Plasma Omega-3 Polyunsaturated Fatty Acids and Healthy Aging
In a cohort of 2,622 adults, higher levels of plasma long-chain omega-3 polyunsaturated fatty acids were associated with a lower risk of unhealthy aging.
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Omega-3 Fatty Acids vs. Olive Oil to Prevent Vascular Events
In a cohort of 15,480 adults with diabetes, there was no significant difference in the risk of serious vascular events when comparing supplementation with 1 g of omega-3 fatty acid vs. an olive oil placebo.
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Organic Food Consumption and Cancer Risk
In this prospective cohort study, high amounts of organic food consumption were associated with a significant decrease in the risk of overall cancer, particularly postmenopausal breast cancer, non-Hodgkin lymphoma, and other lymphomas.
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Ketogenic Diet for Refractory Pediatric Seizures
This retrospective study of 59 children with refractory seizures of genetic etiology investigates the impact of a strict low-carb diet (either modified Atkins or ketogenic diet) on seizure reduction.
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Appropriate Cardiac Testing in an Inappropriate World
This two-part series will look at the rationale and causes of inappropriate testing and how to select the best, most appropriate cardiac test for each patient. The first part will focus on the theory of ordering tests and strategies to minimize unnecessary testing while the second part will focus on when and how to select each individual test given the patient's clinical scenario.
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Decision-Making Capacity in the ICU
A multicenter, one-day prevalence, prospective, observational, double-blind study in 19 ICUs revealed that the decisionmaking capacity of ICU patients was widely overestimated by all clinicians as compared with a capacity score measured by the Mini-Mental Status Examination and the Aid to Capacity Evaluation.
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Acute Kidney Injury With Combination Antibiotics in the Critically Ill
In this retrospective study, a short course (24 to < 72 hours) of combination antibiotic therapy with piperacillin-tazobactam and vancomycin was not associated with an increased risk of acute kidney injury among critically ill patients when compared with other β-lactam and vancomycin combinations.