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Organ Donation: Perspective for the Intensivist
Organ donation and transplantation are important and lifesaving procedures.The complexities of management include determination of death, communication with families, pre-procurement optimization of potential donors, and bereavement support for families.
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Appropriate Cardiac Testing in an Inappropriate World, Part 2: Cardiac Tests
This article addresses specifics of the cardiac testing options, considering their appropriate indications, choices of approach, risks, and costs.
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Darolutamide Tablets (Nubeqa)
Darolutamide should be prescribed to patients with nonmetastatic, castration-resistant prostate cancer.
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Carpal Tunnel Syndrome in the Extreme Elderly
Carpal tunnel syndrome (CTS), when seen in the very elderly, usually is severe and is not reliably diagnosed by ultrasound. Nerve conduction studies and electromyography are the most sensitive and specific tests to make accurate diagnosis of CTS.
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No Antibiotic Prescription Required
Acquisition of antibiotics without a prescription can be easy in the United States.
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CRP and Reduction of Antibiotic Use in Acute Exacerbations of COPD
Point-of-care C-reactive protein testing can safely and effectively reduce antibiotic use in patients with acute exacerbations of COPD.
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Treating Infective Endocarditis in Moderate-Risk Patients
There are patients with a moderate risk of infective endocarditis who may warrant consideration of antibiotic prophylaxis.
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Calcitonin Gene-Related Peptide Targeting Therapies for Migraine
Two randomized clinical trials showed that calcitonin gene-related peptide targeting therapies are effective and safe for primary headache disorders.
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Size Matters Regarding Left Heart Valve Vegetations
An international registry study of left-sided valvular infective endocarditis patients revealed that large vegetations (> 10 mm) are associated with increased mortality at six months, but not if early surgery is performed.
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Blood Pressure Targets in the Elderly
The authors of a large population study found that reducing blood pressure to < 140/90 mmHg is associated with increased mortality, and mortality was highest in those with previous cardiovascular events and age > 80 years.