Clinical
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What Is the Optimal Blood Pressure for Secondary Prevention of Stroke?
Investigators terminated a study early before they could draw any firm conclusions. Thus, there remains a lack of solid evidence to support a firm recommendation regarding optimal blood pressure management for secondary stroke prevention.
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Dapagliflozin Treatment Improves Life Quality for Systolic Heart Failure Patients
Treatment with dapagliflozin for 12 weeks resulted in improved health status, either a reduction in NT-proBNP or improvement in quality of life measures, in systolic heart failure patients with or without type 2 diabetes mellitus.
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Menopausal Hormonal Therapy and Breast Cancer Risk: Are Old Data Relevant to Today’s Practice?
An individual-participant meta-analysis of prospective studies revealed menopausal hormone therapy associated with an elevation in the risk of breast cancer, with the highest risks associated with daily combined therapy.
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Infectious Disease Alert Updates
Lyme Carditis: Any AV Block of Concern; Syphilis Screening in Pregnancy a Must; Deferring INH Until Postpartum in HIV-Positive Women
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Feeding the Microbiota: Complementary Foods Enhance Recovery in Malnourished Children by Modulating the Gut Microbiota
In a series of studies in gnotobiotic animals and malnourished children, incomplete recovery from malnutrition is associated with immature gut microbiota, and complementary foods directed to enhance microbiotal maturity improved recovery from malnutrition.
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Fever of Unknown Origin Due to Cat Scratch Disease
Disseminated cat scratch disease may present as a fever of unknown origin.
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Pneumonia Outbreak in China
A cluster of cases of pneumonia apparently caused by a novel coronavirus has emerged in China.
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Tafenoquine for Malaria Prevention and Relapse Treatment
Tafenoquine is effective for the prevention of all species of malaria and can be used to prevent relapse of Plasmodium vivax and Plasmodium ovale. G6PD status should be evaluated prior to use.
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Taming of the Flu: What’s New for 2020
The 2019-2020 flu season is already among us, and it is imperative that those healthcare practitioners on the frontline have current knowledge of prevention and treatment strategies. Both influenza A and B strains have been identified, and their predominance varies by region and age group.
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Impact of Infectious Disease Consultation for Candidemia
A retrospective cohort study found that infectious disease consultation for patients with candidemia resulted in lower 90-day mortality. This was likely a result of strong adherence to guideline- and evidence-based management and the low number of patients who were not treated.