Clinical
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Can We Liberalize Intrauterine Device Insertion Protocols?
In this retrospective cohort study, the rate of luteal phase pregnancy was 0.4% among 239 women who did not meet pregnancy checklist criteria for intrauterine device insertion.
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Early Loss of Ovarian Function May Increase Risk for Cardiovascular Disease
Natural and surgical menopause appear to be associated with an increased risk for cardiovascular disease.
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A ‘Normal’ Initial ECG?
The ECG in the figure was obtained from a 30-year-old man who was admitted to the hospital to “rule out myocardial infarction.” His symptoms of chest discomfort were thought to be atypical and unlikely to be due to a cardiac etiology. His initial ECG (not shown) was interpreted as normal. Evaluation, including serial troponins and stress testing, were deemed normal. Before sending the patient home, the ECG in the figure was obtained.
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Peanut (Arachis hypogaea) Allergen Powder-dnfp (Palforzia)
This is the first FDA-approved oral immunotherapy for desensitizing peanut allergy in children to help reduce the risk of allergic reactions.
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The Safety and Effectiveness of Pyrethroid Insecticides as the Battle Against Mosquitoes Continues
There is a statistical association between a urine test suggestive of exposure to pyrethroid insecticides and increased mortality over the subsequent 14 years.
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Optimal Antithrombic Therapy After PCI for Atrial Fibrillation Patients
In three subgroups of coronary artery disease patients with atrial fibrillation, apixaban plus a P2Y12 inhibitor provided superior safety and similar efficacy outcomes as treatment with warfarin, aspirin, or both for six months.
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Heart Failure-Exacerbating Medications
In a large, diverse cohort of Medicare patients hospitalized for heart failure exacerbations, almost half were on medications known to exacerbate heart failure; more than one-third were on these agents at discharge.
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Ethics Curriculum Feasible for OB/GYN Faculty
Much ethics education focuses on students and residents, but practicing physicians also need ethics expertise. An ethics and professional curriculum was piloted for faculty in obstetrics and gynecology.
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Testing Detects Hormone Changes Signaling Menopause
Results of a new study established that levels of anti-Müllerian hormone (AMH) can predict when a woman’s final menstrual period will occur. By measuring AMH levels, clinicians have an indicator of how many eggs a woman has remaining. The results of the research were part of the scientific evidence presented to the FDA for the 2018 approval of MenoCheck, an assay kit used to determine menopausal status in women ages 42-62 years.
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Research Reinforces Importance of Tailoring Hormone Therapy
Data from research that examined the use of different oral and transdermal hormone therapy agents and their associations between heart fat accumulation and atherosclerosis progression indicated that in comparison to transdermal estradiol patch, oral conjugated equine estrogen appears to slow the adverse effects of increasing paracardial adipose tissue on the progression of atherosclerosis.