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Epilepsy Management in Primary Care
Epilepsy affects about 50 million people worldwide and is responsible for up to 0.5% of the global burden of disease. There are more than 5 million people diagnosed with epilepsy every year and that number is expected to continue to rise.
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Icosapent Ethyl Capsules (Vascepa)
Icosapent is the first drug approved to reduce the risk of cardiovascular events in patients with established cardiovascular disease and hypertriglyceridemia on maximally tolerated statin therapy.
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CNS Agents Emerge as Frontrunners in FDA-Approved Treatments for Low Libido in Women
Low libido is the most common sexual complaint, affecting up to 38.7% of women, with up to 12.3% also reporting significant distress associated with this condition. Debate continues about how female desire disorders are characterized, diagnosed, and treated.
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The Risk of Endocarditis With Bacteremia
Interrogation of the Danish National Patient Registry revealed bacteremia due to Enterococcus faecalis was most likely to be associated with infective endocarditis; thus, echocardiography is warranted in these patients.
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Fever of Unknown Origin Due to Cat Scratch Disease
Disseminated cat scratch disease may present as a fever of unknown origin.
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Longer Antibiotic Courses for Pneumonia Do Not Improve Outcomes, Do Cause More Adverse Effects
Excess antibiotic therapy did not improve mortality or morbidity outcomes, although each additional antibiotic day was associated with 3% increased odds of antibiotic-associated adverse drug events.
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Laryngeal Injury Is Common After 12 Hours of Intubation
After 12 hours of intubation, most patients showed laryngeal injury, including mucosal ulceration, that led to impaired breathing and voicing 10 weeks after extubation.
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Management of Nontraumatic Intracranial Emergencies: A Clinical Update
This article attempts to provide evidence-based, practical guidelines to the frontline clinician in the nontrauma intensive care setting.
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Efficacy of Class I vs. Class III Antiarrhythmic Drugs in Obese Patients
In an observational cohort of patients with atrial fibrillation, obese patients were less likely than nonobese patients to avoid symptomatic recurrence on sodium channel blocking agents in contrast to a roughly equivalent response in both groups to potassium channel blocking agents.
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Heart Failure-Exacerbating Medications
In a large, diverse cohort of Medicare patients hospitalized for heart failure exacerbations, almost half were on medications known to exacerbate heart failure; more than one-third were on these agents at discharge.