Clinical
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Is Vaginal Progestogen Equivalent to Intramuscular Progestogen for Preventing Preterm Birth in High-Risk Women?
In this open-label, equivalence randomized trial of vaginal progestogen compared to intramuscular progestogens for preventing preterm birth in high-risk women, the difference in the risk of preterm birth at < 37 weeks of gestation between both groups was 3.1% (95% confidence interval, -7.6% to 13.8%), which was within the equivalence margin of 15% used in the study.
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Is Isolated Diastolic Hypertension a Disease?
An analysis of three large prospective databases showed the 2017 American College of Cardiology/American Heart Association revised definition of isolated diastolic hypertension as > 80 mmHg rather than the previous definition of > 90 mmHg resulted in a 5% higher prevalence of diastolic hypertension. This was not significantly associated with cardiovascular disease outcomes.
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What to Do with Large Pericardial Effusions
An observational study of patients with chronic, large, hemodynamically insignificant, C-reactive protein-negative, idiopathic pericarditis in which the majority were treated by pericardiocentesis or surgical drainage showed most patients treated conservatively remained stable. The invasive approach did not reveal an etiology for the effusions.
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Achieving AV Synchrony Without Wires
In the MARVEL 2 prospective study of patients with atrioventricular block treated with a leadless ventricular pacemaker, atrial sensing via an accelerometer-based algorithm was largely successful in establishing atrioventricular synchronous pacing.
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Who Benefits from Primary Prevention ICDs?
Long-term follow-up of SCD-HeFT did not show any benefit in installing implantable cardioverter-defibrillator devices in patients with New York Heart Association class III symptoms or nonischemic cardiomyopathy.
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Valve-in-Valve TAVR for Failed Surgical Prostheses: Short-Term Advantages, Long-Term Unknowns
This large retrospective study of patients undergoing reintervention for failed bioprosthetic aortic valves showed better short-term outcomes with valve-in-valve transcatheter aortic valve replacement vs. redo surgical aortic valve replacement.
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Antibiotic Stewardship: Who’s Responsible?
A joint Pew/AMA survey about resistance and prescribing habits sheds light on provider attitudes and the work ahead.
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National Organization Calls on DEA to Remove Cannabis from Schedule I List
American Heart Association says easing restrictions would allow for better scientific research on drug’s risks and benefits.
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Stress Linked to STIs, Poor Sexual Health of Black Women
Black women with high levels of stress are more likely to experience sexually transmitted infections and poor sexual and reproductive health, according to the authors of new research.
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Disparities Found When Women Visit Reproductive Health Providers
Results of a new study revealed Black women are more likely to be asked about their sexual risk behavior and condom use than are white women in sexual health counseling settings.