Clinical
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Childhood Sleep Difficulties and Adolescent Mental Health
This prospective United Kingdom study involving 13,488 children shows an association between specific early childhood sleep problems and symptoms of psychosis in adolescence. Another specified early childhood sleep problem is associated with symptoms of borderline personality disorder in adolescence.
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Air Pollution and Cognitive Decline
SYNOPSIS: In this large prospective cohort study of subjects in Manhattan, researchers demonstrated an association between exposure to air pollution and decline in cognitive function over time in one cohort, but not the other.
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Healthcare Personnel Hospitalizations and COVID-19 — with Possible Implications for Vaccine Prioritization
During the period of study, 5.9% of individuals hospitalized for COVID-19-related reasons were healthcare providers (HCP), with approximately one-third involving HCP who were not expected to have direct patient contact in the course of their work.
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Norepinephrine Infusion Through Peripheral Intravenous Lines: Is it Safe?
In a large perioperative patient population, norepinephrine infusion through peripheral intravenous lines did not result in any significant adverse events. However, the specific patient population, limited duration of infusion, and hospital setting may limit the generalizability of these findings.
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Do We Really Know the Optimal Oxygen Target in Patients with ARDS?
In the LOCO2 study, a conservative oxygen strategy with SpO2 goals of 88% to 92% was not shown to improve mortality over a liberal oxygen strategy as hypothesized, but rather was found to have a worrisome signal of increased mortality and increased mesenteric ischemia.
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Management of Pulmonary-Renal Syndrome
The role of the intensivist in the management of pulmonary-renal syndrome includes appropriate respiratory support and recognition and management of concurrent infection, hypovolemia, acute anemia, and coagulopathy.
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FDA Issues Emergency Use Authorization for Bamlanivimab
While the search for a vaccine continues, the agency adds to the list of stop-gap therapeutics to battle COVID-19.
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Veterans with PTSD, TBI at Much Higher Risk for Heart Attack
Such patients also more likely to experience first attack at a younger age than the general population.
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AMA Prepares for COVID-19 Vaccine with Coding Updates
Laying the administrative groundwork is an important part of ensuring success for administration of an eventual vaccine.
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Remdesivir Injection (Veklury)
Remdesivir’s benefit appears to be modest, but may be better for those receiving low-flow oxygen.