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Using Sacubitril/Valsartan to Treat Heart Failure with Preserved Ejection Fraction
An analysis of renal outcomes in the PARAGON-HF trial revealed sacubitril/valsartan slows progression of kidney disease in patients with heart failure with preserved ejection fraction compared to valsartan alone.
Virtual Visits and Antibiotic Prescribing
Compared to in-person visits, virtual visits were associated with improved antibiotic prescribing practices for women with uncomplicated urinary tract infections.
Vegan Diets May Cause More Fractures
Living as a vegan or vegetarian is a choice and can benefit one’s health. However, clinicians should educate patients about potential risks, including bone fractures. Appropriate supplementation might prevent these complications.
Honey, Can You Stop Coughing?
Since there is little to offer those with upper respiratory infections, honey represents a low-risk, inexpensive, and easily accessible alternative that seems reasonable to suggest to patients.
Recommendation: Less Major Surgery for Heart Valve Disease
Advancing technology creates opportunities for safer solutions, according to guideline authors.
USPSTF: Screen At-Risk Adolescents, Adults for Hepatitis B
Advocacy group says recommendations are too narrow.
AAFP, CDC Promote Immunizations Among Minority Populations
Groups recruiting family medicine practices for two initiatives.
A Mobile Interventional Stroke Team (MIST) Shows Promise in Performing Rapid Thrombectomy
Since 2015, when multiple international trials were reported showing clear benefit for mechanical thrombectomy in patients with large vessel occlusions, this treatment has been the standard of care. However, the speed of treatment remains paramount for good outcomes, and different models have been developed around the world in different geographic settings.
Ticagrelor, a New Antiplatelet Agent, Shows Promise in Secondary Prevention of Ischemic Stroke
Ticagrelor is an antiplatelet agent that works by reversibly binding to P2Y12 adenosine diphosphate receptors on platelets, similar to the mechanism of action of clopidogrel. However, it is a direct-acting drug, and not a pro-drug, and does not need to be enzymatically converted to be active, like clopidogrel.
Medical Therapy vs. Carotid Endarterectomy in Patients with Asymptomatic Carotid Stenosis
Since the pivotal trials demonstrating the benefit of endarterectomy vs. medical therapy many years ago, there has been significant improvement in the risk factors for atherosclerosis, including better treatment of blood pressure and diabetes, as well as improved antiplatelet medication regimens and high-potency statins.