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This analysis of mitral surgery after failed transcatheter edge-to-edge repair demonstrates high rates of valve replacement as opposed to repair. Surgical mortality was higher than predicted but was significantly lower in high-volume centers.
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An analysis of the ASPREE database showed that with almost five years of follow-up, statins are not associated with cognitive decline or dementia in a large group of elderly subjects in whom multiple tests of cognition were performed serially.
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Semaglutide can be prescribed as an adjunct to a low calorie diet and increased physical activity for chronic weight management in overweight and obese adults.
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In addition to identifying several patient risk factors for contamination of blood culture specimens, the authors also highlighted various adverse clinical and financial adverse effects.
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Cholinesterase inhibitors are one of the few drug classes approved by the FDA to treat patients with Alzheimer’s disease. This study shows a long-term benefit in slowing the decline of cognition, but it is unclear if there is any benefit in quality of life.
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Disparate public health messaging from political officials, news media, and online outlets has occurred throughout the COVID-19 pandemic in the United States. Some have wanted to ascribe lower rates of compliance with public health guidance to political affiliation.
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Researchers found many survivors of COVID-19 exhibited significant loss of health six months after their acute illness, with greater risk associated with severity of the acute infection.
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An analysis of the utility of implanted loop recorders to detect subclinical atrial fibrillation in high-risk individuals showed that among common arrhythmia-compatible symptoms, only palpitation was predictive of discovering episodes of atrial fibrillation.
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Right after the FDA issued an emergency use authorization for one drug, feds pressed pause on distributing another.
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But randomized trials are needed to better detail long-term risk-benefit ratio.