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Anticoagulation Plus Antiplatelet Therapy in Chronic Atherosclerosis
An analysis of the COMPASS trial for the secondary endpoint of mortality showed the combination of low-dose rivaroxaban and aspirin significantly lowered the all-cause mortality rate vs. low-dose aspirin alone.
No Harm in a Morning Cup of Joe
Habitual coffee consumption was inversely associated with a lower risk of cardiac arrythmia.
Statins, Cognitive Decline, and Dementia
An analysis of the ASPREE database showed that with almost five years of follow-up, statins are not associated with cognitive decline or dementia in a large group of elderly subjects in whom multiple tests of cognition were performed serially.
COVID-19 Vaccination: The Heart of the Matter
The occurrence of myocarditis after receipt of COVID-19 vaccines is most frequent in young men and generally benign, with rapid resolution only through supportive care. Careful analysis indicates the benefit of vaccination outweighs the risk in all groups for whom the vaccine is recommended.
‘Empowered Relief’ Approach Could Help Patients with Limited Time, Resources
Researchers offer one brief, blended skills-building session for low back pain management that might be cheaper and easier to access than other multisession options.
Jury Still Out on Convalescent Plasma
One year after the FDA issued an emergency use authorization, investigators are struggling to draw firm conclusions about the efficacy of this solution against COVID-19.
FDA Gives Full Approval to Pfizer’s COVID-19 Vaccine
A significant milestone in the ongoing battle against the pandemic.
Treatment of Seizures After Spontaneous Intracerebral Hemorrhage
The reported incidence of post-stroke seizures varies and appears to have a higher incidence following hemorrhagic stroke. Post-stroke seizures have been associated with a greater length of hospitalization, increased mortality, and complications. This study compared four seizure prophylaxis strategies to determine the greatest net benefit for patients with spontaneous intracerebral hemorrhage. There was a better outcome with short-term antiepileptic medication use compared to long-term use.
Cortical Lesions Correlate with Disability in Patients with Multiple Sclerosis
In a long-term, 30-year follow-up study of a cohort of patients with multiple sclerosis who presented with clinically isolated syndrome, the investigators found that, among the variables assessed, the presence of cortical lesions had the highest association with long-term physical and cognitive disability.
Proteomics: A New Method to Understand the Influence of Genetic Variation on Disease Pathogenesis
The combination of genome-wide association studies with the analysis of messenger ribonucleic acid and unique proteins in the brain, cerebrospinal fluid, and plasma can shed new light on our understanding of the genetic risks for the development of various neurological diseases.