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rt-PA Stroke Trials: Pooled Analysis and Opinion
Thrombolysis with intravenous rt-PA (IVrt-PA) is an effective treatment for strokes due to acute cerebral ischemia. This analysis of pooled data confirms that the sooner rt-PA is given to stroke patients, the greater the benefit, especially if started within 90 minutes. The results suggest a potential benefit beyond 3 hours but with a potential for an increased risk of death. -
Correction
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Aspirin Dosage in ACS
The dose of aspirin after discharge for acute coronary syndromes may affect the 6-month clinical course. -
Long-Term Aspirin Therapy
Long-term treatment with aspirin is associated with a progressive diminution in platelet sensitivity to the drug. -
Policosanol: A Natural Alternative for Lipid Management?
Sasser H, Barringer T. Policosanol: A natural alternative for lipid management? Altern Med Alert 2004;7(4):37-41. -
Clinical Briefs: Antibacterial Soaps and Infectious Disease
Greenfield RH. Antibacterial soaps and infectious disease. Altern Med Alert 2004;7(4):47-48. -
Clinical Briefs: Safety of Niacin
Greenfield RH. Safety of niacin. Altern Med Alert 2004;7(4):48. -
Patient Handout: Cholesterol and Coronary Heart Disease
Cholesterol and Coronary Heart Disease. Altern Med Alert 2004;7(4):S1-S2. -
Pharmacology Watch: Estrogen Found to Not Affect Heart Disease, Breast Cancer
The NIH has halted the estrogen-alone wing of the Womens Health Initiative a year before its scheduled end. -
Clinical Briefs in Primary Care Supplement