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  • The Rip Van Winkle Diet, Part II

    Sleep restriction (to 4 hours a night) resulted in increased appetite, increased cortisol levels, lowered TSH levels, worsened glucose tolerance and lower heart rate variability compared with sleep extension (to 12 hours a night) in young healthy volunteers.
  • Reducing Normal Blood Pressure Benefits Patients with Coronary Artery Disease

    A new randomized trial using either a calcium channel blocker or an ACE inhibitor to lower systolic blood pressure to the low 120s prevented cardiac events in patients with coronary artery disease compared with systolic blood pressures around 130.
  • Increase in the Reservoir of Community-Acquired MRSA, With Implications for Hospital-Acquired Infection

    Over a 7-year period, there was a dramatic increase in the isolation of community-acquired MRSA in the San Francisco area. Molecular typing showed movement of community-acquired strains into hospitals.
  • Pharmacology Update: Lanthanum Carbonate Tablets (FosrenalTM)

    A new non-aluminum, non-calcium, phosphate binder has been approved by the FDA.
  • Clinical Briefs

    In an attempt to clarify the role of early intensive glycemic control, newly diagnosed type 2 diabetes patients were treated with insulin by means of an insulin pump on an inpatient basis for two weeks, after which they were discharged.
  • ECG Review: What Would You Ask the Patient?

    The consecutive rhythm strips seen in the Figure were obtained from a 73-year-old man with a history of ischemic cardiomyopathy. QRS widening is the result of underlying bundle branch block. In view of the atrial activity seen in these rhythm strips, what would you want to ask the patient?
  • Pharmacology Watch - ACE Inhibitors and Receptor Blockers: Which is Inferior?

    The first head-to-head comparison study of an ACE inhibitor and an angiotensin receptor blocker, to assess renoprotective effects in type 2 diabetes, has shown that the drugs are comparable in their benefit.
  • Clinical Briefs in Primary Care

    Toenail Chromium in Men With Diabetes and Cardiovascular Disease; Combination of Fenofibrate and Rosiglitazone and HDL Cholesterol; Outcomes for Patients with Diet-Controlled Diabetes; Erythromycin and the Risk of Sudden Death; Acute Hyperglycemia, Mood, and Cognitive Performance in Type 2 Diabetics; Psychosocial Risk Factors and Risk of Acute MI.
  • Clinical Briefs in Primary Care

    Functional Decline in Peripheral Arterial Disease; Topical Capsaicin for Chronic Pain; Topical Tacrolimus Therapy for Vitiligo; US Prevalence and Impact on Axillary Hyperhidrosis; Mortality and Incidence of Cancer During 10-Year Follow-Up of the Scandinavian Simvastatin Survival Study (4S); Effects of Extended Outpatient Rehabilitation After Hip Fracture.
  • Clinical Briefs in Primary Care

    Folate Therapy and In-Stent Restenosis and Coronary Stenting; Quinapril Reduces Markers of Oxidative Stress in the Metabolic Syndrome; Donepezil in Patients with Alzheimers; Effect of the Dietary Approaches to Stop Hypertension Diet and Reduced Sodium Intake on Blood Pressure Control; Methylprednisolone, Valacyclovir, or the Combination for Vestibular Neuritis; Improved Plasma Glucose Control, Whole-Body Glucose Utilizations, and Lipid Profile on a Low-Glycemic Index Diet in Type 2 Diabetic Men.