Clinical
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Post-TAVR Patients with Atrial Fibrillation Bleed Less on Vitamin K Antagonists vs. Edoxaban
In this randomized trial of post-transcatheter aortic valve replacement patients with atrial fibrillation, edoxaban was noninferior to vitamin K antagonists with regard to a composite of adverse endpoints, but was associated with a higher rate of major bleeding.
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New Treatment for Hypertrophic Obstructive Cardiomyopathy
A study of the echocardiographic characteristics of symptomatic patients with obstructive hypertrophic cardiomyopathy treated with mavacamten showed a persistent 30-week improvement in several key pathophysiologic characteristics.
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List of Possible Cancer-Causing Agents Grows Longer
Six water disinfection byproducts, plus a flame retardant and a bacterial infection, now considered potential human carcinogens.
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National Alzheimer’s Plan Updated with New Focus on Healthy Aging
Feds add sixth goal in the ninth version of this annually released report.
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Stroke Patients Visit EDs Often After Discharge from Hospital
Repeat visits to the ED are quite common, even for patients who experienced mild or moderate strokes and are managing their conditions at home. This suggests home care models for these complex patients are important to evaluate and modify, if needed, to improve long-term care outcomes.
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Post-Exercise Premature Ventricular Contraction, or Aberrancy?
The ECG in the figure is a post-exercise tracing. There are four wider and slightly early occurring beats in the long lead rhythm strips. Are these beats premature ventricular contractions or premature atrial contractions conducted with aberration?
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Nirmatrelvir and Ritonavir Tablets (Paxlovid)
The FDA has issued an emergency use authorization for the first oral regimen for the treatment of COVID-19.
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Incidence, Prevalence, and Long-Term Consequences of Small Fiber Neuropathy
Small fiber neuropathy (SFN) associated with diabetes and other causes is more likely to progress to large-fiber polyneuropathy, deteriorate faster, and cause worse disability vs. slow progression with idiopathic SFN.
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Coronary CT Angiography in the General Population
Coronary artery CT angiography in asymptomatic, middle-aged subjects without known coronary artery disease showed coronary atherosclerosis is common but mostly mild and appears in women after a 10-year delay.
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Fish Consumption, Omega-3 Fatty Acids, and Cardiovascular Disease
Is there enough scientific evidence to suggest associations between fish consumption and risk of cardiovascular disease (or of mortality) among people who consume fish vs. those who do not?