Clinical
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Social Isolation Among Older Adults Is Associated with Higher Rates of Disability and Mortality Post-ICU Stay
In this observational cohort study drawn from the National Health and Aging Trends Study, social isolation among older adults admitted to the intensive care unit was associated with greater disability burden and higher one-year mortality rates after critical illness.
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Invasive Aspergillosis Is an Independent Predictor of Mortality in Mechanically Ventilated Patients with SARS-CoV-2 Infection
This multicenter cohort study found a high incidence of invasive aspergillosis in mechanically ventilated patients with SARS-CoV-2 pneumonia.
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Vasopressin and Steroids Increase Likelihood of Return of Spontaneous Circulation with Unclear Longer-Term Effects
In this multicenter, randomized clinical trial, the combination of vasopressin and methylprednisolone improved the rate of return of spontaneous circulation in patients with in-hospital cardiac arrest but had no significant effect on longer-term outcomes.
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Practice Guidelines for Difficult Airways
The American Society of Anesthesiologists has released updated guidelines on the management of the difficult airway.
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Researchers Observe Connection Between E-Cigarette Use and Erectile Dysfunction
More bad news for this “safe” alternative to traditional nicotine delivery systems.
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Inclisiran Injection (Leqvio)
Inclisiran can be prescribed as an adjunct to diet and maximally tolerated statin therapy for adults with heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease who required additional low-density lipoprotein cholesterol lowering.
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Adverse Effects of Electronic Cigarettes on the Disease-Naïve Oral Microbiome
A robust metagenomic comparison study of the effects of electronic cigarettes on oral microbiomes suggested that the unique aerosol component of electronic cigarettes poses increased risk to development of oral cavity disease.
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Plant-Based Diets and Menopausal Hot Flashes
Women randomized to a low-fat, vegan diet including one-half cup of cooked whole soybeans daily experienced a reduction in total hot flashes of 79% vs. 49% in the control group over 12 weeks of observation.
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Infections Before Age 20 Years Increase the Risk of Multiple Sclerosis
Researchers found patients diagnosed with infection in adolescence were at higher risk for multiple sclerosis, even after exclusion of infectious mononucleosis, pneumonia, and central nervous system infection.
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New Dietary Guidance to Improve Cardiovascular Health: Meeting People Where They Are
The American Heart Association emphasizes the importance of an overall lifetime heart-healthy diet and the vital role of nutrition early in life.