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Rapid Magnetic Resonance Imaging vs Radiographs for Patients with Low Back Pain; Effectiveness of Anticholinergic Drugs Compared with Placebo in the Treatment of Overactive Bladder; A Randomized Trial of a Low Carbohydrate Diet for Obesity
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The FDA recently approved gefitinib, an inhibitor of tyrosine kinase activity of the epidermal growth factor receptor, for the treatment of non-small-cell lung cancer.
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Compared with abstention, consumption of 1-6 drinks weekly of alcoholic beverages was associated with a lower risk of dementia among adults older than 65 years.
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A warfarin initiation nomogram that uses 10 mg as a starting dose achieves a therapeutic INR more rapidly than one using a 5-mg starting dose.
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Over a 5-year period, the incidence of developing sleep-disordered breathing (AHI > 5 events/hr) is about 37%, about 7% per year. With aging, male gender and body mass index (BMI) lose importance as risk factors for obstructive sleep apnea.
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The vasomotor flush is viewed as the hallmark of the female climacteric, experienced to some degree by most postmenopausal women. In the Massachusetts Womens Health Study, the incidence of hot flushes increased from 10% during the premenopausal period to about 50% just after cessation of menses.
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Following radiation therapy, adjuvant extrafascial hysterectomy decreased the risk of relapse for patients with bulky stage IB cervical cancer without improving survival.
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Birth weight discordancy of > 15% for same sex and > 30% for different sex confer greatest risk of adverse perinatal outcomes in the absence of abruption.
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The data in this case-control study of combined estrogen plus progestin therapy revealed an increased risk of breast cancer, particularly invasive lobular tumor, regardless of whether the progestin component was taken sequentially or continuously.