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Losartan therapy of hypertensive patients with LVH resulted in greater LVH regression as compared to atenolol independent of blood pressure control and baseline ECG findings.
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A Strategy to Reduce Cardiovascular Disease by More Than 80 Percent;
Pearly Penile Papules: Still No Reason for Uneasiness; The Epidemiology
of Major Depressive Disorder; Urinary Tetrahydroaldosterone as a Screen
for Aldosteronism; Finasteride and Prostate Cancer; Impermeable Bed
Covers in Patients with Allergic Rhinitis
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The frequency with which patients are hospitalized for atrial fibrillation is increasing dramatically with a large proportion of the increase due to an increased number of elderly patients in the population. Part of this increase may also be due to changes in management strategies for atrial fibrillation. Inpatient observation for initiation of antiarrhythmic therapy or for anticoagulation is now commonly recommended, particularly in elderly patients.
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In hypertensive patients without clinically evident vascular disease, losartan was more effective than atenolol in preventing future vascular events independent of blood pressure control.
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The DANAMI-2 investigators, representing 29 hospitals and a patient base reflecting 62% of the Danish population, have reported on a trial assessing whether randomization to either fibrinolytic therapy or transport to an interventional facility results in differing major cardiovascular rates following acute ST elevation myocardial infarction (STEMI).
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Stroke with no determined cause, or cryptogenic stroke (CS), accounts for nearly 40% of all ischemic strokes. Traditionally, it has been held that CS carries a more benign prognosis than other stroke subtypes. However, until this recent study, the long-term risk of recurrent stroke in this large segment of the stroke population had never been prospectively studied.
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This study suggests that the risk conferred by an inherited thrombophilia for ischemic stroke is likely to be low overall and almost nonexistent in some ethnic groups such as individuals of African or African-Caribbean descent.
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Genetic investigations have made considerable progress in identifying mutations associated with familial amyotrophic lateral sclerosis (ALS). The identification of genetic alterations in patients with sporadic ALS, however, has lagged behind. The present study is a major advance in investigating the etiology of ALS.
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The FDA has approved vardenafil (LevitraBayer and GlaxoSmithKline) for the treatment of erectile dysfunction in men. Vardenafil joins sildenafil (Viagra) as the only 2 drugs approved for this indication in this country.
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Thymectomy, though widely recommended for the treatment of autoimmune myasthenia gravis, remains a treatment without controlled prospective studies to support its role. Such a trial has been recommended by the American Academy of Neurology and is being developed.
