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Intensive Monitoring for Asymptomatic Atrial Fibrillation Did Not Prevent Strokes

Screening with an implantable loop recorder resulted in dramatically higher rates of atrial fibrillation detection and ensuing anticoagulation, but without a significant decrease in risk of stroke or systemic embolism by six years of follow-up.

Cost to Treat U.S. Patients with Rare Diseases Likely Underestimated

NIH, FDA, other groups form consortium to speed gene therapy development.

What Is the ‘Bix Rule?’

The ECG in the figure was obtained from a middle-aged man with a history of exertional chest pain and dyspnea. How would one interpret this tracing? Does the red arrow in lead II show a sinus P wave?

Atogepant Tablets (Qulipta)

Atogepant can be prescribed to prevent episodic migraine in adults.

Progression of Coronary Calcium on Statin Treatment

In those treated with statins vs. those who were not, statins decreased plaque volume in plaques with little or no calcium (plaque regression) and increased calcium density without changes in plaque volume in calcified plaques (plaque stabilization).

Adjuvanted Zoster Vaccine: Persistent Protection

The adjuvanted recombinant zoster vaccine efficacy is high and persistent, with apparent plateauing at > 84% four to six years after vaccination.

First-Line Therapy for Hypertension

When comparing angiotensin-converting enzyme inhibitors and angiotensin receptor blockers (ARBs) to treat hypertension, researchers observed no difference in major cardiovascular events — but a better safety profile for ARBs.