Clinical Publication
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How Many Abnormal Findings?
No history was available for the tracing in the figure. There are at least seven ECG findings to note. How many can you identify?
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Sotagliflozin Tablets (Inpefa)
Sotagliflozin tablets can be prescribed to lower the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visits among adults living with heart failure or type 2 diabetes mellitus, chronic kidney disease, and other cardiovascular risk factors.
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A Primer on Excessive Daytime Sleepiness and Narcolepsy
Many new drugs are coming on the market to treat daytime sleepiness, as well as insomnia, as the prevalence of sleep disorders continues to grow in modern society. Clinicians should familiarize themselves with these disorders and the various ways to treat them safely.
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Does Running Prevent Coronary Artery Disease?
In this cross-sectional review of the Master Athlete Heart study, the authors found lifelong endurance sport participation was not associated with a more favorable coronary plaque composition vs. a healthy lifestyle. Lifelong endurance athletes exhibited more coronary plaques.
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Prescribing the Internet to Prevent Dementia
In an ongoing longitudinal survey of a nationally representative sample of dementia-free adults age 50 to 64.9 years, regular internet users experienced approximately half the risk of dementia compared with non-regular users.
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Using an Online e-Health Program to Improve Postpartum Depression
This study demonstrated that combined use of universal depression screening and MomMoodBooster2, a cognitive behavioral therapy-based e-health program, were effective tools for treating women with depression in the perinatal period.
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Influenza Vaccination May Temporarily Aid Cardiovascular Event Prevention
Researchers studied English patients with an acute cardiovascular event who received an influenza vaccine in the same 12-month period and compared that to the 120-day period after vaccination and the rest of the year. They observed those vaccinated were less likely to experience an acute cardiovascular event for 120 days after vaccine vs. the rest of the year.
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Walk! A Long-Term Observational Investigation of Knee Osteoarthritis
An observational study of more than 1,000 individuals aged 50 years and older with knee arthritis revealed that regular walking for exercise correlates with fewer reports of new knee pain and slower disease progression, as verified by radiographic evidence at eight-year follow-up.
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Is Screening First-Degree Relatives of Cardiomyopathy Patients Worthwhile?
An observational study of screening first-degree relatives of patients with dilated cardiomyopathy revealed 14% will show either dilated left ventricles, low left ventricular function, or both. These findings are more common if the relatives have been diagnosed with hypertension or are obese, but their frequency is not altered by sex or race.
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Timing of Anticoagulation Administration Following Atrial Fibrillation-Associated Stroke
A prospective, blinded, randomized study of early vs. later administration of oral anticoagulation after ischemic stroke in patients with atrial fibrillation calibrated by cerebral imaging showed no significant difference in 30-day outcomes.