Clinical Publication
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Coronary CT Angiography in Patients with Type 2 Myocardial Infarction
In an observational, single-center study of patients with type 2 myocardial infarction who underwent coronary CT angiography, researchers reported fewer than half had a significant anatomic stenosis (50% or greater), but only 26% had a hemodynamically significant lesion by CT fractional flow reserve.
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Risk of Incidental Coronary Calcium on Chest CT Scans
A deep learning-derived algorithm for measuring coronary artery calcium scores in non-ECG-gated, non-contrast chest CT scans ordered for non-cardiac reasons was predictive of death and adverse atherosclerotic cardiovascular events. This may provide an opportunity for earlier prevention interventions.
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What Coronary Artery Calcium Score Signifies Secondary Prevention?
A large registry study of individuals without known cardiovascular disease but with known coronary artery CT calcium scores showed those with an Agatston score higher than 300 are at risk of experiencing major cardiac events similar to patients with known cardiovascular disease over five years.
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Medical Therapy Before Mitral Valve Edge-to-Edge Repair for Congestive Heart Failure Patients
This study of U.S. registry of mitral transcatheter edge-to-edge repair data revealed a minority of patients undergoing this procedure experience optimized medical therapy, with wide variations across sites.
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Running to Keep Ahead of Coronary Artery Disease
In this cross-sectional review of the Master Athlete Heart study, the authors found lifelong endurance sport participation was not associated with a more favorable coronary plaque composition vs. a healthy lifestyle. Lifelong endurance athletes exhibited more coronary plaques.
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Exploring the Relationship Between Alcohol and Cardiovascular Events
Researchers reported consuming two to 14 alcoholic drinks per week was associated with fewer major adverse cardiovascular events, which the authors noted could be explained in part by less stress-related neural activity demonstrated on PET and CT scans.
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Can Cognitive Behavioral Therapy Help with Insomnia?
In this randomized clinical trial, telephone-administered cognitive behavioral therapy for insomnia significantly outperformed education alone in alleviating insomnia and reducing daytime fatigue in older adults with osteoarthritis pain.
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Is the Irregularity a Problem?
Interpreting ECGs without the benefit of any history always is challenging. Such is the case with the figure in this article, which manifests significant irregularity.
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COVID-19 Vaccine, 2023-2024 Formula (Comirnaty, Spikevax)
The newest vaccines target XBB.1.5, which is no longer the dominant circulating variant, but they offer protection against XBB.1.16 and more distant variants (e.g., EG.5.1, FL.1.1.1, and BA.2.86).
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Steroids and Pneumonia — So Meta?
In a multicenter, randomized, placebo-controlled trial, hydrocortisone lowered mortality rates among patients with severe community-acquired pneumonia.