Clinical Publication
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Studying Patients at High Risk for Death in the ICU Can Give Them a Voice and Help Clinicians Understand Their Concerns
Using a multiple-source approach, this study showed that when given a voice, patients at high risk of dying in the intensive care unit express variable logistical, spiritual, physical, psychological, and existential concerns that clinicians should consider and address.
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Coronary CT Angiography in Patients with Type 2 MI
In an observational, single-center study of patients with type 2 myocardial infarction who underwent coronary computed tomography (CT) angiography, researchers reported fewer than half had a significant anatomic stenosis (50% or greater), but only 26% had a hemodynamically significant lesion by CT fractional flow reserve.
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Atorvastatin vs. Rosuvastatin in Patients with Coronary Artery Disease
A large trial of moderate doses of rosuvastatin vs. atorvastatin in patients with coronary artery disease has shown that both drugs are equivalent at reducing major adverse cardiovascular and cerebral events, but rosuvastatin is associated with higher rates of new-onset diabetes and cataract surgery.
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Searching for Step Counts: Defining Goals for Daily Exercise
A systematic review and meta-analysis of studies of the association of step counts and cadence with all-cause mortality and cardiovascular events showed the benefits in these outcomes are statistically significant, at about 2,600 steps/day and peak at about 8,000 steps/day. Also, faster step cadence augments these benefits.
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Can Turmeric Help Handle Heartburn?
In a randomized controlled trial, curcumin demonstrated comparable efficacy to omeprazole in treating dyspepsia and acid reflux.
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Empowered Relief vs. CBT vs. Health Education for Low Back Pain
This randomized clinical trial involving adults with chronic low back pain demonstrates that a single session of a pain management class, when compared to a full course of cognitive behavioral therapy, yields noninferior (clinically on par) outcomes in pain catastrophizing and several other measures at the three-month follow-up.
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Exploring the Mixed Messages of Research Regarding Alcohol
The authors of a large systematic review and meta-analysis concluded there is no health benefit from moderate alcohol intake.
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Can Antidepressants Help Patients Manage Chronic Pain?
Antidepressant medications have been widely used for treating a variety of chronic pain disorders, but strong evidence to support their efficacy is lacking. Some patients may respond, but available data do not help us determine which agents may be helpful in a specific type of chronic pain condition.
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Oils, Fats, and Mortality: Examining Fats’ Effects on Health and Longevity
This comprehensive prospective study reveals that, compared to non-consumers, individuals using butter and/or margarine have an elevated total mortality rate, while those incorporating canola and/or olive oil into their diets exhibit a reduced total mortality risk.
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Aberrant Conduction?
How should one interpret the ECG in the figure? Is the rhythm most likely to be a re-entry supraventricular tachycardia with aberrant conduction?