Clinical Publication
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Insulin Resistance at the Blood-Brain Barrier in Alzheimer’s Disease
Alterations in cerebrovascular insulin receptor isoform levels were associated with Alzheimer’s disease pathology and caused deficits in insulin signaling at the level of the blood-brain barrier.
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Multivitamin-Mineral Supplementation vs. Cocoa Extract for Cognition
Researchers followed participants for three years and determined daily cocoa supplement use was not associated with cognitive enhancement in older adults, whereas a multivitamin supplement was associated with significant cognitive benefits.
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Zavegepant Nasal Spray (Zavzpret)
Zavegepant can be prescribed to treat migraine, with or without aura, in adults.
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Double BBB, or Complete AV Block?
The ECG in the figure is from a woman who complained she had been experiencing chest pain for several days. What is the rhythm? Is there complete AV block?
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Moderate-Intensity Exercise OK for Statin Users with Muscle Pain
The go-to drug therapy patients use to lower their bad cholesterol levels can cause muscle pain for some, but researchers found moderate exercise would not exacerbate that pain.
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The Connection Between Bereavement, Sleep, and Inflammation
This study of the association of sleep disturbance with more markers of inflammation in widows and widowers compared to controls revealed self-reported sleep disturbances are more strongly correlated with increased markers of inflammation in bereaved individuals.
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Prosocial vs. Self-Rewarding Behavior and Their Effects on Stress Recovery
Two randomized, controlled studies were created to examine the effects of giving gifts vs. receiving gifts after stressful situations. They both revealed the “giving” group reported recovering from stress faster, showing more happiness, showing less desire, and reporting no significant difference in relaxation compared to the “receiving” group and a control group.
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Healthy Lifestyle Behaviors Linked to Slower Memory Decline
In a population-based, prospective cohort study of 29,000 Chinese adults, researchers found healthy lifestyle was associated with slower memory decline, even in the presence of the apolipoprotein E4 allele.
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Self-Treatment of Recurrent Benign Paroxysmal Positional Vertigo
Using a cell phone-based app, self-treatment of recurrent benign positional paroxysmal vertigo was feasible and effective in most patients.
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Does COVID Vaccination Prevent Car Crashes?
In a large study, lack of COVID vaccination was associated with more incidents of car crash injuries.