Clinical Publication
RSSArticles
-
Dyeing to Death: Examining the Risks of Red 40 and High-Fat Diets
This study exploring colorectal cancer development reveals that Allura Red AC (Red 40), a synthetic dye prevalent in many American diets, causes significant deoxyribonucleic acid damage and colonic inflammation in mice, especially when combined with a high-fat diet.
-
Identifying Risk Factors for Young-Onset Dementia
In this large, population-based prospective cohort study, the investigators identified 15 risk factors that have strong associations with young-onset dementia. Modifications of these risk factors might delay the onset of, or prevent the development of, young-onset dementia.
-
Caring After COVID: Is Brain Impairment After Severe COVID-19 Worse Than Other Diseases?
The authors of this prospective cohort study with matched controls found that long-term brain health following severe COVID-19 hospitalization was impaired but was similar to hospitalization from other severe diseases.
-
Birch Triterpenes Topical Gel (Oleogel-S10) (Filsuvez)
The U.S. Food and Drug Administration has approved a treatment for wounds associated with junctional epidermolysis bullosa and dystrophic epidermolysis bullosa not specific to a particular mutation. Birch triterpene is a botanical drug substance composed of a mixture of pentacyclic triterpenes (e.g., botulin, lupeol, betulinic acid, erythrodiol, and oleanolic acid) formulated as a topical gel.
-
Buprenorphine May Be an Effective Alternative to Full Opioids for Pain in the ICU
In a small, single-center, retrospective, propensity-matched cohort study examining enteral oxycodone vs. sublingual buprenorphine in a critically ill population, pain control was equivalent, indicating that sublingual buprenorphine may be an effective and appropriate alternative.
-
Long-Term Follow-Up Confirms Efficacy of Invasive Strategy in Very Old Patients with Non-ST-Elevation ACS
In this long-term analysis of patients in the After Eighty Study, with a mean age of 85 years and non-ST-elevation acute coronary syndrome, an invasive strategy showed a reduction in a composite endpoint of major adverse cardiovascular events and was associated with a significant improvement in event-free survival compared with a conservative approach.
-
Cumulative Number of Head Strikes Contributes to the Development of CTE
A recent study evaluated the connection between head impact and chronic traumatic encephalopathy (CTE) in male athletes and found that the total number and severity of head impacts throughout life better predicted CTE than the number of symptomatic concussions.
-
Are You Sitting Down to Read This? You May Want to Stand Up
A large prospective cohort study demonstrated that prolonged sitting at work increases the risk for all-cause and cardiovascular disease mortality, but even short periods of physical activity throughout the day may help mitigate the negative effects.
-
Identifying and Responding to Potential Cases of Human Trafficking in the Primary Care Setting
This paper aims to equip the primary care provider with the knowledge and skills to identify and respond effectively to potential cases of human trafficking in a primary care setting. When seeking care, individuals caught up in trafficking are most likely to present to an emergency room or urgent care, but about 40% go to private practices or clinics. An astute primary care provider has a unique opportunity to educate, intervene, or assist a patient at this point, should the individual be looking for this type of intervention.
-
Effect of Atrial Fibrillation Catheter Ablation on Psychological Well-Being
A randomized trial of catheter ablation vs. medical therapy for atrial fibrillation (AF) patients has shown that anxiety and depression scores are significantly reduced by catheter ablation and are associated with decreases in AF burden and improved physical symptoms.