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In daily clinical practice, OAC was only given to a minority (30%) of AMI patients with AF, despite the fact that OAC was associated with a 29% relative and 7% absolute reduction in 1-year mortality after adjustment for confounding variables. The results emphasize the importance of OAC treatment for AF after AMI.
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Oral amiodarone prophylaxis of atrial tachyarrhythmias after cardiac surgery is effective and well tolerated.
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There is a wide variation in presentation and course of ARVD patients, which can likely be explained by the genetic heterogeneity of the disease.
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The high rates of acute vascular events outside the coronary arterial territory and the steep rise in event rates with age in all territories have implications for prevention strategies, clinical trial design, and the targeting of funds for service provision and research.
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Fenofibrate did not significantly reduce the risk of the primary outcome of coronary death or non-fatal MI. It did reduce total cardiovascular events, mainly due to fewer non-fatal myocardial infarctions and revascularizations.
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Long-term vasodilator therapy with either nifedipine or enalapril changed neither the hemodynamic burden of severe aortic regurgitation nor reduce or delay the need for valve replacement surgery in asymptomatic patients with chronic severe aortic regurgitation and normal LV function.
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Volume outcome data for percutaneous coronary interventions (PCI) was largely collected and reported in the balloon angioplasty era. Thus, this report from New York state's PCI reporting system from 1998 to 2000 is of interest. This database of over 100,000 cases, which can be adjusted for severity of illness, was interrogated for 3 outcomes: in-hospital mortality, same-day coronary artery bypass surgery (CABG), and same-stay CABG.
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An early invasive strategy did not result in an expected differential in the primary end point.
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Lithium can unmask latent Brugada syndrome by blockade of susceptible cardiac sodium channels.
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Women have a higher risk than men for atrial fibrillation related thromboembolism that is independent of the presence of other risk factors.
