Clinical Cardiology
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Hypothyroidism and PCI Outcomes
Hypothyroidism is common in patients undergoing percutaneous coronary interventions in a multivariate adjusted observational study was associated with worse long-term outcomes.
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Optimal Blood Pressure in Patients Presenting with Aortic Stenosis
A post-hoc analysis of patients suffering from mild to moderate aortic stenosis in a study of low-density lipoprotein cholesterol lowering showed that the optimal blood pressure for the best survival was 130-139/70-90 mmHg.
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An Important Update in the Bare-metal vs. Drug-eluting Stent Debate
This randomized trial showed no difference between contemporary drug-eluting stents and bare-metal stents with regard to death and myocardial infarction, while drug-eluting stents demonstrated an advantage in both repeat revascularization and stent thrombosis at six years of follow-up.
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Has the Benefit of Prophylactic ICDs Been Overestimated Among Those Suffering From Nonischemic Cardiomyopathy?
Prophylactic implantable cardioverter defibrillator implantation does not provide mortality benefit for nonischemic heart failure patients.
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Screening for Coronary Artery Disease Is Underused in Heart Failure
In a large retrospective cohort of patients hospitalized for new-onset heart failure, the majority did not receive testing for ischemic heart disease.
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Ventricular Tachycardia Ablation vs. Escalation of Antiarrhythmic Drugs in Ischemic Cardiomyopathy
Among patients with an ischemic cardiomyopathy and an implantable cardioverter defibrillator (ICD), catheter ablation was more effective than escalated antiarrhythmic drug therapy in reducing the rate of death at any time or ventricular tachycardia storm or ICD shocks after a 30-day blanking period.
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The Double-edged Sword of Public Mortality Reporting
Since the exclusion of cardiogenic shock from public mortality reporting in New York in 2006, rates of intervention in these patients have risen dramatically. However, these rates remain below those in non-reporting states, suggesting continued reluctance to treat the highest-risk patients due to public reporting.
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Is There HOPE for Blood Pressure Targets in Primary Prevention?
A large randomized trial of fixed-dose antihypertensive treatment in patients at intermediate risk of cardiovascular events with systolic blood pressure < 160 mmHg showed no difference in outcomes vs. placebo.
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Should We SPRINT to Lower Blood Pressure Targets?
ABSTRACT & COMMENTARY: Here's insight into an intensive treatment that resulted in 33% fewer major adverse cardiovascular events.
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Early Adverse Events Post-PCI Carry Greatest Mortality Risk
About one in eight patients undergoing successful PCI will suffer MI, stent thrombosis or a clinically relevant bleeding event within two years.