Clinical Cardiology
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MRI for Patients With Pacemakers and Defibrillators
Performing an MRI on patients with pacemakers and defibrillators that were not MRI-conditional was not associated with any clinically significant changes in device parameters.
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Clinical Context and Outcomes in Stress Cardiomyopathy
An analysis of the International Takotsubo Registry showed that long-term mortality is similar to that observed in patients with acute coronary syndromes but varies widely depending on the triggering event.
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Tafamidis Improves Survival in Transthyretin Cardiac Amyloidosis
Treatment with tafamidis in transthyretin amyloid cardiomyopathy patients produced reductions in all-cause mortality and cardiovascular hospitalizations. This was the first medical therapy to demonstrate improved survival for patients with this condition.
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MitraClip Falls Short in First Randomized Trial Specific to Functional Mitral Regurgitation
The authors of a recent study concluded that percutaneous mitral valve repair with MitraClip did not significantly alter rates of death and heart failure hospitalization at one year over medical therapy alone.
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Who Really Needs Intensive Blood Pressure Control?
A patient baseline characteristics level analysis of the SPRINT and ACCORD trials resulted in the creation of a simple algorithm for identifying high-risk patients who experienced fewer major cardiac events without increased serious adverse events from intensive blood pressure therapy.
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Instantaneous Wave-free Ratio vs. Fractional Flow Reserve: Defining Low-risk Population for Deferral of PCI
Researchers recently found that deferral of percutaneous coronary intervention based on fractional flow reserve and instantaneous wave-free ratio is equally safe, with a low one-year major adverse cardiac event rate of approximately 4%.
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Substance Abuse and Myocardial Infarction
Among patients ≤ 50 years of age with first myocardial infarctions, use of cocaine or marijuana increased the likelihood of an ST-segment elevation myocardial infarction and the subsequent risk of all-cause and cardiovascular mortality.
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Risk of Infective Endocarditis Revisited
In a comparison of patients with infective endocarditis (IE) and either bicuspid aortic valve (BAV) or mitral valve prolapse (MVP) vs. other IE patients at high or low to moderate risk of IE, BAV and MVP patients were more likely to exhibit viridans streptococci group infections of suspected odontogenic origin and cardiac complications at similar rates to high-risk patients.
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Home-based Detection of Undiagnosed Atrial Fibrillation
In patients with risk factors for atrial fibrillation, screening with a self-applied wearable ECG patch resulted in significantly increased rates of new atrial fibrillation diagnoses within four months, along with greater use of anticoagulants and healthcare resources.
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Canagliflozin Reduces Risk of Heart Failure Hospitalizations for Diabetic Patients
In type 2 diabetes mellitus patients with a higher risk of cardiovascular disease, canagliflozin lowered the risk of cardiovascular death or heart failure hospitalization. Patients with pre-existing heart failure may experience even greater benefit.