Clinical Cardiology
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Positive Outcomes With One Month of Dual Antiplatelet Therapy After PCI
One month of dual antiplatelet therapy (DAPT) followed by single antiplatelet therapy with clopidogrel was noninferior to 12 months of DAPT following percutaneous coronary intervention with drug-eluting stents.
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Reducing Mortality in Stable Ischemic Heart Disease Patients
A multivariate analysis of a large registry of patients with stable ischemic heart disease revealed that beta-blocker use was associated with lower mortality only when prescribed in the first year after acute myocardial infarction.
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Do Antianginal Agents Prevent Revascularization Procedures?
For patients with stable ischemic heart disease, adding either ranolazine or calcium channel blockers to nitrate or beta-blocker therapy reduced the incidence of subsequent revascularization and costs vs. beta-blocker or nitrate therapy alone or in combination.
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Keep Calm and Compress On, But Do Not Hold Your Breath Too Long
In a recent analysis, using any CPR was associated with significant improvement in 30-day survival, with slightly better outcomes associated with standard CPR over compression-only CPR.
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Workplace Violence, Bullying Associated With Cardiovascular Disease Risk
In a 12-year follow-up of surveyed Scandinavian employees, reported workplace violence and bullying increased the risk of future cardiovascular disease of a magnitude similar to other recognized cardiovascular disease risk factors.
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Are Calcium Channel Blockers Needed for Radial Artery Grafts?
A combined analysis of six trials comparing radial artery grafts vs. saphenous vein grafts for coronary bypass surgery revealed that patients taking calcium channel blockers for at least one year experienced fewer major cardiac events and fewer radial graft occlusions than those not so treated.
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Mildly Elevated Pulmonary Arterial Pressure Associated With Higher Mortality Rate
In a large cohort of patients referred for echocardiography, an estimated right ventricular systolic pressure > 30 mmHg was associated with higher mortality rates.
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Is Earlier Better With Oral P2Y12 Inhibition in STEMI Patients?
In a large retrospective analysis of patients in Sweden treated with primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction, a propensity-matched group of patients who received oral P2Y12 inhibitors at initial medical contact did not show improved outcomes vs. those receiving these agents at the time of PCI.
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Early vs. Delayed Cardioversion: A Nonshocking Result
For patients presenting to an ED with recent-onset atrial fibrillation, using rate control and outpatient cardioversion only as needed was associated with a high rate of spontaneous conversion within 48 hours of arrhythmia onset and noninferior short-term outcomes compared to immediate cardioversion in the ED.