Clinical Cardiology
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Efficacy of the Ross Procedure in Young Adults with Aortic Valve Disease
Young patients who underwent the Ross procedure recorded high rates of survival and low rates of reintervention long term.
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ECG Abnormalities in Elite Male and Female Athletes
A study of elite international soccer athletes of both sexes revealed women more often recorded what would be considered abnormal ECGs — only to return normal echocardiograms. This knowledge is especially valuable when treating those who have recovered from COVID-19.
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New Treatment for Postural Orthostatic Tachycardia Syndrome
A study of ivabradine in patients with the common hyperadrenergic subtype of the postural orthostatic tachycardia syndrome led to slower standing heart rates, lower plasma norepinephrine levels, and improved quality of life after one month.
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PFO Closure for Resistant Migraines: Finding an Elusive Link
A meta-analysis of two randomized trials of patent foramen ovale closure in resistant migraine showed a significant benefit in three of four clinical endpoints.
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Intracranial Plaque Rupture and Stroke
An MRI study of cerebral circulation in patients with embolic stroke of undetermined etiology showed evidence of atherosclerotic plaque in most patients, supporting the theory that unstable intracranial artery plaques play an etiologic role in embolic stroke.
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Is Empagliflozin Safe in Combination with a Neprilysin Inhibitor for Heart Failure?
A prespecified subgroup analysis of heart failure patients with reduced ejection fraction who were on neprilysin inhibitors before empagliflozin was administered (vs. those not on neprilysin inhibitors) showed the reduction in mortality and hospital admissions for heart failure were not attenuated by concurrent neprilysin use.
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Are Beta-Blockers Still Relevant After a Myocardial Infarction?
A large, contemporary, nationwide, observational study of post-myocardial infarction beta-blocker administration shows that after three months, there were no beneficial effects on adverse cardiovascular events to continued beta-blocker use.
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Statins and Muscle Symptoms: Cause and Effect?
An analysis of three large simvastatin trials revealed muscle symptoms on simvastatin are common, but true myopathy is rare and can be predicted by evaluating certain risk factors for its development, which can help guide patient management.
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Is Effective Transcatheter Tricuspid Repair Becoming a Reality?
In two trials of transcatheter devices treating tricuspid regurgitation, the authors observed high efficacy and low adverse event rates.
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Transitioning Patients from ECLS to Durable MCS
A registry of patients transitioned from extracorporeal life support to durable mechanical circulatory support was used to derive a tool predicting one-year survival.