Clinical Cardiology
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Does Electrode Position Affect the Results of Cardioversion?
A randomized trial of anteroposterior vs. anterolateral electrode positioning for the biphasic energy cardioversion of atrial fibrillation showed the anterolateral positioning is most effective.
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Coronary Calcium Score Zero: Are You Home Free?
Among those with a coronary calcium score of 0 after a median follow-up of 16 years, current cigarette smoking, diabetes, and hypertension were independently associated with the development of atherosclerotic cardiovascular disease.
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CABG Wins Again for Multivessel Disease
In this contemporary trial of revascularization for multivessel disease, fractional flow reserve-guided percutaneous coronary intervention failed to meet noninferiority guidelines vs. coronary artery bypass grafting.
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Significance of Flail Mitral Leaflet and Wall-Impinging Regurgitant Flow
Using cardiac MRI as a gold standard, the presence of a flail mitral leaflet or a wall-impinging mitral regurgitant jet on transthoracic echocardiography were associated with severe mitral regurgitation, but not diagnostic of it.
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Jugular Venous Pressure by Bedside Ultrasound
Using a handheld point-of-care ultrasound device to estimate right atrial pressure from images of the jugular vein resulted in a higher imaging success rate vs. visual inspection and a reasonably accurate estimation, especially in those with elevated right atrial pressures.
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Importance of Exercise Testing-Associated Ventricular Ectopy
A study of asymptomatic subjects without known cardiovascular disease undergoing treadmill exercise testing and followed for a mean of 20 years showed high-grade premature ventricular contractions during exercise recovery (but not during exercise) are predictive of subsequent cardiovascular mortality.
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Post-TAVR Patients with Atrial Fibrillation Bleed Less on Vitamin K Antagonists vs. Edoxaban
In this randomized trial of post-transcatheter aortic valve replacement patients with atrial fibrillation, edoxaban was noninferior to vitamin K antagonists with regard to a composite of adverse endpoints, but was associated with a higher rate of major bleeding.
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New Treatment for Hypertrophic Obstructive Cardiomyopathy
A study of the echocardiographic characteristics of symptomatic patients with obstructive hypertrophic cardiomyopathy treated with mavacamten showed a persistent 30-week improvement in several key pathophysiologic characteristics.
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Is a New Right Bundle Branch Block a Sign of Coronary Artery Disease?
For asymptomatic subjects without known cardiac or renal disease, coronary lesions by CT angiography are more frequent in those with right bundle branch block vs. those without.
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Earlier Coronary Artery Bypass Grafting After Ticagrelor Discontinuation Is Safe
In a trial that included acute coronary syndrome patients treated with ticagrelor, undergoing coronary bypass surgery within two to three days was noninferior to the guideline-recommended five to seven days regarding severe bleeding.